Results 201 to 210 of about 120,525 (339)

Scaling‐up the Bioconversion of Lignin to 2,4‐Pyridinedicarboxylic Acid With Engineered Pseudomonas putida for Bio‐Based Plastics Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT 2,4‐pyridinedicarboxylic acid (PDCA) is a promising bio‐based compound to substitute petroleum‐derived terephthalic acid in plastics. It is produced through the microbial conversion of lignin substrates with engineered microorganisms like Pseudomonas putida.
Jan Seeger   +6 more
wiley   +1 more source

A Bioprocess Engineering Approach to Boost Selection of Fully Segregated Transformants in Cyanobacteria

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cyanobacteria are photoautotrophic microorganisms with significant applications in biotechnology. Although many cyanobacteria, including Picosynechococcus sp. (formerly called Synechococcus sp.) PCC 11901 (Picosynechococcus) and Synechocystis sp.
Cecilia Salvagnini   +7 more
wiley   +1 more source

Scalable, High‐Density Expansion of Human Mesenchymal Stem Cells on Microcarriers Using the Bach Impeller in Stirred‐Tank Reactors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT This paper describes the results of process developmental experiments to achieve higher cell densities in the manufacturing of hMSCs using the novel Bach impeller in a stirred‐tank bioreactor. Engineering experiments have previously shown that the Bach impeller represents an efficient mixing device that suspends particles in fluids at low ...
Tom A. Wyrobnik   +5 more
wiley   +1 more source

Large-Scale Production of Expandable Hepatoblast Organoids and Polarised Hepatocyte Organoids From hESCs Under 3D Static and Dynamic Suspension Conditions. [PDF]

open access: yesCell Prolif
Wu H   +14 more
europepmc   +1 more source

Interpretable‐AI‐Based Model Structural Transfer Learning to Accelerate Bioprocess Model Construction

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Determining accurate kinetic models for new biochemical systems is time‐intensive, requiring experimental data collection, model construction, validation, and discrimination. Traditional black‐box machine learning‐based transfer learning methods leverage prior knowledge but lack interpretability and physical insights.
Alexander W. Rogers   +4 more
wiley   +1 more source

Sabin inactivated polio vaccine upstream process development using fixed-bed bioreactor technology. [PDF]

open access: yesVaccine
Hamidi A   +12 more
europepmc   +1 more source

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