Results 211 to 220 of about 111,398 (363)
Evaluation of hollow fiber bioreactors as an alternative to murine ascites production for small scale monoclonal antibody production [PDF]
Lynn Jackson+3 more
openalex +1 more source
A synthetic platform for developing recombinant adeno‐associated virus type 8 producer cell lines
Abstract Recombinant adeno‐associated virus (rAAV) is one of the most widely used viral vectors for gene therapy. It is used in very high doses for the treatment of many diseases, making large‐scale production for clinical applications challenging. We have established a synthetic biology‐based platform to construct stable production cell lines, which ...
Yu‐Chieh Lin+5 more
wiley +1 more source
Charting the landscape of the environmental exposome
We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei+6 more
wiley +1 more source
The Properties of the Multistage Bioreactor Constructed by the LB Technique
Michihiro Ohnishi+2 more
openalex +1 more source
The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes [PDF]
JM Rosen+3 more
openalex +1 more source
Abstract Monitoring cell culture is crucial for gaining a deeper understanding of processes and ensuring the production of safe and high‐quality products. The capability to measure in real time several parameters of interest can be achieved with Raman spectroscopy.
Célia Sanchez+6 more
wiley +1 more source
Anaerobic Digestion of Sewage Sludge by Membrane Separated Bioreactor.
Hidenori Aya, Katsuyuki NAMIKI
openalex +2 more sources
A study on the convergence of observer-based kinetics estimators in stirred tank bioreactors [PDF]
Rui Oliveira+3 more
openalex +1 more source
Abstract One strategy to enhance the production of biological therapeutics is using transient perfusion in the preculture (N‐1 stage) to seed the production culture (N stage) at ultra‐high cell densities (>10 x 106 viable cells/mL). This very high seeding density improves cell culture performance by shortening the timeline and/or achieving higher final
Lucas Lemire+5 more
wiley +1 more source