Results 231 to 240 of about 126,870 (331)

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

open access: yesBiotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu   +6 more
wiley   +1 more source

Electrocatalytic CO2 Reduction Coupled to Formate Fermentation: An Electro‐Bio Cascade Approach in Biocompatible Electrolytes

open access: yesChemistry – A European Journal, EarlyView.
CO2 utilization in industrial biotechnology: Rational design of a process cascade for electrochemical CO2 reduction linked with formate fermentation, supporting robust cell growth and high biomass yields. ABSTRACT Integration of electrochemical CO2 reduction with microbial fermentation enables conversion of CO2 into valuable chemicals but poses ...
Luciana Vieira   +8 more
wiley   +1 more source

Performance Comparison between Semi‐Automated and Manual Cell Counting for Animal Cell Culture

open access: yesChemie Ingenieur Technik, EarlyView.
Following ISO 20391‐2:2019 guidelines, manual and semi‐automated cell counting performances were compared using validation parameters from ICH Q2(R1). Specificity, linearity, and repeatability served as key validation parameters in the evaluation of total cell density and cell viability of CHO‐K1 cells using trypan blue exclusion staining.
Selina Uhlendorff   +3 more
wiley   +1 more source

Application of vibrational spectroscopies as process analytical techniques for monitoring fermentation and the conversion of lignocellulosic biomass by oleaginous filamentous fungi. [PDF]

open access: yesMicrob Cell Fact
Dzurendova S   +13 more
europepmc   +1 more source

Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism

open access: yesFood Bioengineering, EarlyView.
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing   +3 more
wiley   +1 more source

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