Results 231 to 240 of about 126,870 (331)
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu +6 more
wiley +1 more source
CFD Modeling of Shear-Rate Distribution in a Bubble Column Bioreactor: Influence of Bubble Diameter and Lift Force. [PDF]
Silva ACB +3 more
europepmc +1 more source
CO2 utilization in industrial biotechnology: Rational design of a process cascade for electrochemical CO2 reduction linked with formate fermentation, supporting robust cell growth and high biomass yields. ABSTRACT Integration of electrochemical CO2 reduction with microbial fermentation enables conversion of CO2 into valuable chemicals but poses ...
Luciana Vieira +8 more
wiley +1 more source
Special Issue "Molecular Studies on Plant and Plant In Vitro Systems Secondary Metabolism". [PDF]
Marchev AS.
europepmc +1 more source
Performance Comparison between Semi‐Automated and Manual Cell Counting for Animal Cell Culture
Following ISO 20391‐2:2019 guidelines, manual and semi‐automated cell counting performances were compared using validation parameters from ICH Q2(R1). Specificity, linearity, and repeatability served as key validation parameters in the evaluation of total cell density and cell viability of CHO‐K1 cells using trypan blue exclusion staining.
Selina Uhlendorff +3 more
wiley +1 more source
Application of vibrational spectroscopies as process analytical techniques for monitoring fermentation and the conversion of lignocellulosic biomass by oleaginous filamentous fungi. [PDF]
Dzurendova S +13 more
europepmc +1 more source
Performance evaluation of ultrasonic transducer in a mist bioreactor by different nutrient media
Ali Fadavi +2 more
openalex +1 more source
Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing +3 more
wiley +1 more source

