Results 231 to 240 of about 120,525 (339)

Expansion of induced pluripotent stem cells under consideration of bioengineering aspects: part 2. [PDF]

Appl Microbiol Biotechnol
Teale MA, Schneider SL, Seidel S, Krasenbrink J, Poggel M, Eibl D, Sousa MFQ, Eibl R.   +7 more
europepmc   +1 more source

Degradation of p -nitrophenol and pentachlorophenol mixtures by Sphingomonas sp. UG30 in soil perfusion bioreactors [PDF]

, 2000
Tom Alber, Mike Cassidy, Robert M. Zablotowicz, J. T. Trevors, H Lee   +4 more
openalex   +1 more source

Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies

Biotechnology Progress, EarlyView.
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester, Thomas R. Blanda, Marena Trauger, Rachel Thompson, Neil Templeton   +4 more
wiley   +1 more source

Novel Respirometry Measurement and Comparison of Monod Kinetic Constants and Methanogen Concentrations for 27 Full-Scale Anaerobic Bioreactors. [PDF]

Water Environ Res
Benn N, Martins A, Zitomer DH.
europepmc   +1 more source

A digital shadow of CAR T cell expansion in a perfusion bioreactor: Informing optimal harvest times for autologous cell therapy

Biotechnology Progress, EarlyView.
Using online metabolite data from the first few days of a bioreactor run, the digital shadow can forecast the cell concentration in real‐time with an accuracy of 13% (standard deviation ≈ 6%). These predictions can guide the optimal harvest time of CAR T cells for subsequent re‐infusion into the patient.
Joseph R. Egan, Núria Marí‐Buyé, Elia Vallejo Benítez‐Cano, Miquel Costa, Linda Wanika, Michael J. Chappell, Ursula Schultz, Jelena Ochs, Manuel Effenberger, David Horna, Qasim Rafiq, Stephen Goldrick   +11 more
wiley   +1 more source

Skeletal Muscle Tissue Engineering: From Tissue Regeneration to Biorobotics. [PDF]

Cyborg Bionic Syst
Cordelle MZ, Snelling SJB, Mouthuy PA.
europepmc   +1 more source

High Density Culture of Streptococcus lactis 527 Using Electro-microfiltration Bioreactor.

, 1996
Masaru Hakoda, Atsushi Enomoto, Kozo Nakamura   +2 more
openalex   +2 more sources

A recurrent neural network for soft sensor development using CHO stable pools in fed‐batch process for SARS‐CoV‐2 spike protein production as a vaccine antigen

Biotechnology Progress, EarlyView.
Abstract Fed‐batch recombinant therapeutic protein (RTP) production processes utilizing Chinese Hamster Ovary (CHO) cells can take a long period of time (>10 days). Within this period, not all critical features may be measured routinely, and in fact, some are only measured once the process is terminated, complicating decision making.
Sebastian‐Juan Reyes, Robert Voyer, Yves Durocher, Olivier Henry, Phuong Lan Pham   +4 more
wiley   +1 more source

Characterizing the effect of impeller design in plant cell fermentations using CFD modeling. [PDF]

Sci Rep
Manickavasagam VM, Anupindi K, Bhatt N, Srivastava S.   +3 more
europepmc   +1 more source

Impact of bioreactor process parameters and yeast biomass on Raman spectra

Biotechnology Progress, EarlyView.
Abstract In‐line Raman spectroscopy combined with chemometric modeling is a valuable process analytical technology (PAT) providing real‐time quantitative information on cell culture compounds. Considering that compound quantification through chemometric models depends on pre‐processing to maintain consistent changes in intensity at certain wavenumbers,
Maarten Klaverdijk, Mehrab Nemati, Marcel Ottens, Marieke E. Klijn   +3 more
wiley   +1 more source