Results 331 to 340 of about 111,398 (363)
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Current Opinion in Biotechnology, 1997
Recent papers have described new bioreactor designs. Most innovations addressed either oxygen transfer, shear induced by stirring, control of water activity in organic phase systems or waste biotreatment. Innovations made during the past year were reported in mainly three areas: bioreactor designs for increases in oxygen transfer and decreases in shear
, Deshusses +3 more
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Recent papers have described new bioreactor designs. Most innovations addressed either oxygen transfer, shear induced by stirring, control of water activity in organic phase systems or waste biotreatment. Innovations made during the past year were reported in mainly three areas: bioreactor designs for increases in oxygen transfer and decreases in shear
, Deshusses +3 more
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2010
Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use.
Eibl-Schindler, Regine, Eibl, Dieter
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Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use.
Eibl-Schindler, Regine, Eibl, Dieter
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International Journal of Biochemistry, 1994
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
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1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne +6 more
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1998
Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Bioreactors in Tissue Engineering
Technology and Health Care, 2010A bioreactor can be defined as a device that uses mechanical means to influence biological processes. In tissue engineering bioreactors can be used to aid in the in vitro development of new tissue by providing biochemical and physical regulatory signals to cells and encouraging them to undergo differentiation and/or to produce extracellular matrix ...
Niamh Plunkett, Fergal J. O'Brien
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Current Opinion in Biotechnology, 1997
A very wide range of methods has recently been employed to selectively partition fermentation products, substrates, or other metabolites to achieve an overall improvement in bioprocess performance. Techniques ranging from extraction and gas stripping to electrokinetic methods have been used to favorably influence the microenvironment of cells being ...
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A very wide range of methods has recently been employed to selectively partition fermentation products, substrates, or other metabolites to achieve an overall improvement in bioprocess performance. Techniques ranging from extraction and gas stripping to electrokinetic methods have been used to favorably influence the microenvironment of cells being ...
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Hydrometallurgy, 1999
A survey of the literature on biohydrometallurgical topics revealed that the papers devoted to bioreactors amount to less than 5 % of the total and refers mainly to the analysis of the performance and m design guidelines of stirred tank and of bubble column machines, the so-called Pachuca tanks.
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A survey of the literature on biohydrometallurgical topics revealed that the papers devoted to bioreactors amount to less than 5 % of the total and refers mainly to the analysis of the performance and m design guidelines of stirred tank and of bubble column machines, the so-called Pachuca tanks.
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2020
Enzymes are pliable systems and core cellular components allowing the performance of several processes. They can also be utilized as "green" synthetic factories to generate bioactive therapeutic, diagnostic or theranostic compounds. Methods to enable the mapping of enzyme substrates as well as the understanding of the interactions of the formed ...
Chatzikonstantinou A. V. +8 more
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Enzymes are pliable systems and core cellular components allowing the performance of several processes. They can also be utilized as "green" synthetic factories to generate bioactive therapeutic, diagnostic or theranostic compounds. Methods to enable the mapping of enzyme substrates as well as the understanding of the interactions of the formed ...
Chatzikonstantinou A. V. +8 more
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2011
In this article, membrane bioreactor principles and applications will be discussed. In particular, the properties and applications of bioartificial hybrid membrane systems used in biotechnological and medical fields will be emphasized. In the first part, we focus on general aspects of membrane bioreactors, including some highlights on membrane ...
L Giorno, L De Bartolo, E Drioli
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In this article, membrane bioreactor principles and applications will be discussed. In particular, the properties and applications of bioartificial hybrid membrane systems used in biotechnological and medical fields will be emphasized. In the first part, we focus on general aspects of membrane bioreactors, including some highlights on membrane ...
L Giorno, L De Bartolo, E Drioli
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Biotechnology and Bioengineering, 1990
AbstractThe fluid dynamic design and characterization of a low mechanical stress agitator and bioreactor vessel for large‐scale bioprocessing using anchorage dependent mammalian cells is considered. The complex and fragile nature of mammalian cells puts stringent constraints on the design of agitators for stirred tank bioreactors. Traditional agitators
S. Schreck +2 more
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AbstractThe fluid dynamic design and characterization of a low mechanical stress agitator and bioreactor vessel for large‐scale bioprocessing using anchorage dependent mammalian cells is considered. The complex and fragile nature of mammalian cells puts stringent constraints on the design of agitators for stirred tank bioreactors. Traditional agitators
S. Schreck +2 more
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