A Hierarchical Observer for a Non–Linear Uncertain CSTR Model of Biochemical Processes
The problem of estimation of unmeasured state variables and unknown reaction kinetic functions for selected biochemical processes modelled as a continuous stirred tank reactor is addressed in this paper.
Czyżniewski Mateusz, Łangowski Rafał
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Towards synthetic biological approaches to resource utilization on space missions. [PDF]
This paper demonstrates the significant utility of deploying non-traditional biological techniques to harness available volatiles and waste resources on manned missions to explore the Moon and Mars. Compared with anticipated non-biological approaches, it
Arkin, Adam P+3 more
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A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte+6 more
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This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis+5 more
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Successful Treatment of an MTBE-impacted Aquifer Using a Bioreactor Self-colonized by Native Aquifer Bacteria [PDF]
A field-scale fixed bed bioreactor was used to successfully treat an MTBE-contaminated aquifer in North Hollywood, CA without requiring inoculation with introduced bacteria. Native bacteria from the MTBE-impacted aquifer rapidly colonized the bioreactor,
Baker, Jeffrey M.+7 more
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Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
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Dimensionnement et extrapolation des bioréacteurs sur base de paramètres physiologiques : cas de la production de lipase par Yarrowia lipolytica [PDF]
Bioreactor scale-up and design on the basis of physiologically relevant parameters: application to the production of lipase by Yarrowia lipolytica.
Kar, T.+3 more
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Effect of cytostatic drug presence on extracellular polymeric substances formation in municipal wastewater treated by membrane bioreactor [PDF]
The effect of the cyclophosphamide and its mean metabolites on extracellular polymeric substances (EPS) formation was investigated. Two lab-scale membrane bioreactors were followed in parallel (one with the cytostatic drugs, the second without ...
Albasi, Claire+5 more
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Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
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Sequential biological and photocatalysis based treatments for shipboard slop purification: A pilot plant investigation [PDF]
This study investigated the treatment of a shipboard slop containing commercial gasoline in a pilot plant scale consisting of a membrane biological reactor (MBR) and photocatalytic reactor (PCR) acting in series. The MBR contributed for approximately 70%
Bellardita M.+6 more
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