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Deep phenotyping to understand hearing and hearing disorders: Protocol for a feasibility study. [PDF]
PLoS ONEGlobally, hearing loss affects around 1.5 billion people, while tinnitus is estimated to impact around 740 million. More research is urgently needed to address the challenges presented by hearing loss, tinnitus, and other hearing-related conditions.
Ruth V Spriggs +6 more
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A Single Bacterium Capable of Oxidation and Reduction of Iron at Circumneutral pH
Microbiology Spectrum, 2021 Fe(II)-oxidizing microorganisms and Fe(III)-reducing microorganisms, which drive the biogeochemical Fe cycle on the Earth’s surface, are phylogenetically and ecologically diverse.
Shingo Kato, Moriya Ohkuma
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Stem Cell Research, 2021 The ALDH2 mutation (ALDH2*2) is caused by an amino acid substitution ALDH2 rs671 G>A (pE487K) which reduces ALDH2 enzyme activity. When individuals with the ALDH2 mutation consume alcohol, accumulating acetaldehyde in the blood can cause reddened face ...
Huai-En Lu +5 more
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Microorganisms, 2022 Spent mushroom substrates (SMSs) can be developed as a biofertilizer through composting. Here, we investigated the dynamics of bacterial and fungal communities during commercial composting and the effect of swine and poultry manure on their communities ...
Wan-Rou Lin +3 more
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Deletion of NTH1 and HSP12 increases the freeze–thaw resistance of baker’s yeast in bread dough
Microbial Cell Factories, 2022 Background The intracellular molecule trehalose in Saccharomyces cerevisiae may have a major protective function under extreme environmental conditions. NTH1 is one gene which expresses trehalase to degrade trehalose.
Bo-Chou Chen, Huan-Yu Lin
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Scientific Reports, 2022 A novel type of agarose gel microcapsule (AGM), consisting of an alginate picolitre sol core and an agarose gel shell, was developed to obtain high-quality, single-cell, amplified genomic DNA of bacteria.
Hiroyoshi Aoki +5 more
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Microorganisms, 2021 The purpose of this study was to investigate the ability of ascomycetous yeasts to assimilate/ferment d-fructose. This ability of the vast majority of yeasts has long been neglected since the standardization of the methodology around 1950, wherein ...
Rikiya Endoh +2 more
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Resonance Raman analysis of intracellular vitamin B12 analogs in methanogenic archaea
Analytical Science Advances, 2022 Methanogenic archaea (methanogens) are microorganisms that can synthesize methane. They are found in diverse environments ranging from paddy fields to animal digestive tracts to deep‐sea hydrothermal vents.
Nanako Kanno +4 more
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Biomolecules, 2023 The CRISPR-Cas system has been widely used for genome editing due to its convenience, simplicity and flexibility. Using a plasmid-carrying Cas protein and crRNA or sgRNA expression cassettes is an efficient strategy in the CRISPR-Cas genome editing ...
Bo-Chou Chen, Yu-Zhen Chen, Huan-Yu Lin
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Stress Response of Mesosutterella multiformis Mediated by Nitrate Reduction
Microorganisms, 2020 Bacterial stress responses are closely associated with the survival and colonization of anaerobes in the human gut. Mesosutterella multiformis JCM 32464T is a novel member of the family Sutterellaceae, an asaccharolytic bacterium.
Nao Ikeyama +2 more
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