Results 211 to 220 of about 2,382,076 (302)

Spatio‐Temporal Diversity of Calcium Activity in Microglia

open access: yesGlia, Volume 74, Issue 3, March 2026.
Ca2+ activity mostly occurs in microglial processes and stays localized. When it spreads, it often shows a directional bias and is constrained by branch points. Activity strongly relies on P2Y12 receptors and is shaped by neuronal activity. ABSTRACT Microglia, the brain's innate immune cells, possess complex, highly motile branched processes. These act
Hiroshi Horiuchi   +3 more
wiley   +1 more source

A large-scale comparison of clinical outcomes to IBD therapies in White and South Asian ethnicities. [PDF]

open access: yesEClinicalMedicine
Balarajah S   +11 more
europepmc   +1 more source

Novel therapeutic strategy targeting STMN1 using chlorambucil‐conjugated pyrrole–imidazole polyamide in small cell lung cancer

open access: yesInternational Journal of Cancer, Volume 158, Issue 5, Page 1336-1347, 1 March 2026.
What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa   +23 more
wiley   +1 more source

Impact of Incidental High Ocean Waves on Topographical Changes in the Adélie Penguin Colony at Edmonson Point on the Northern Victoria Land Coast, Antarctica

open access: yesNew Zealand Journal of Geology and Geophysics, Volume 69, Issue 1, March 2026.
Natural disaster‐driven environmental changes can have both direct and indirect effects on seabird breeding and nesting conditions. Edmonson Point, located on the Victoria Land coast in the Ross Sea, hosts around 3000 pairs of Adélie penguins (Pygoscelis adeliae), divided between coastal and hillside subcolonies differing in topography.
Youmin Kim   +3 more
wiley   +1 more source

Genetic overlap between functional impairment and depression and anxiety symptom severity: evidence from the GLAD Study. [PDF]

open access: yesPsychol Med
Skelton M   +25 more
europepmc   +1 more source

Extensive phenotyping and genome‐wide analysis of grain number‐related traits in a diverse wheat core collection

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Bread wheat (Triticum aestivum L.) is one of the most important staple crops globally. Grain number per spikelet (GPS) is an important yield component in wheat. It is influenced by floret number per spikelet (FPS) and floret fertility. Through three consecutive years of observation of FPS, GPS, and floret fertility per spikelet (FFPS) in a ...
Zhuo Su   +4 more
wiley   +1 more source

Clinical Utility and Cost-Effectiveness of Pretreatment NUDT15 Pharmacogenetic Testing to Prevent Thiopurine-Induced Myelosuppression: A Genotype-First Reverse Phenotyping Cohort Study Within the UK NIHR Inflammatory Bowel Disease Bioresource. [PDF]

open access: yesAliment Pharmacol Ther
Roberts C   +34 more
europepmc   +1 more source

Degradation of Dyes by Fungi: A Bibliometric Study and Bibliographic Review

open access: yesEnvironmental Quality Management, Volume 35, Issue 3, Spring 2026.
ABSTRACT The degradation of dyes from textile effluents is considered a major challenge due to their high potential for environmental contamination and health risks due to their toxicity. In this sense, the use of fungi for the degradation of these compounds is reported in the literature as an ecological alternative with great potential.
Antonio Marcelo Magalhães Gomes   +4 more
wiley   +1 more source

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