Results 111 to 120 of about 5,348,273 (263)

Designing Cross-Domain Sustainability Instruction in Higher Education: A Mixed-Methods Study Using AHP and Transformative Pedagogy

Sustainability
This study proposes an interdisciplinary instructional model tailored for Functional Ecological Carbon (FEC) education, combining Electronic, Mobilize, and Ubiquitous (E/M/U) learning principles with the Practical Transformational Teaching Method (PTtM).
Wan-ting Xie, Shang-Tse Ho, H. Lin
semanticscholar   +1 more source

Cognitive load and performance of health care professionals in donning and doffing PPE before and after a simulation-based educational intervention and its implications during the COVID-19 pandemic for biosafety.

Le infezioni in medicina, 2020
The Personal Protective Equipment (PPE) is essential to avoid the COVID-19 spread to health care workers. Its use can be difficult, posing a high risk of contamination, mainly during doffing, then with the risk of becoming infected.We conducted a prospective before-and-after design that used clinical simulation as a research methodology in a clinical ...
Diego Andrés, Díaz-Guio, Alejandra, Ricardo-Zapata, Jeniffer, Ospina-Velez, Gabriel, Gómez-Candamil, Santiago, Mora-Martinez, Alfonso J, Rodriguez-Morales   +5 more
openaire   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

AaeAP2a, a scorpion-derived antimicrobial peptide, combats carbapenem-resistant Acinetobacter baumannii via membrane disruption and triggered metabolic collapse

Frontiers in Microbiology
IntroductionCarbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant global health challenge owing to its high mortality rates and widespread antibiotic resistance.
Weiyu Luo, Weiyu Luo, Weiyu Luo, Weiyu Luo, Liuwei Zhang, Liuwei Zhang, Haolei Gao, Haolei Gao, Huiying Li, Huiying Li, Xiaofeng Li, Xiaofeng Li, Yuliang Wen, Yuliang Wen, Huarun Sun, Huarun Sun, Bolin Hang, Bolin Hang, Longfei Zhang, Longfei Zhang, Wei Zhang, Wei Zhang, Xuehan Liu, Xuehan Liu, Ruibiao Wang, Ruibiao Wang, Bo Wen, Bo Wen, Jiyuan Shen, Jiyuan Shen, Chunling Zhu, Chunling Zhu, Yueyu Bai, Lei Wang, Lei Wang, Ke Ding, Ke Ding, Jianhe Hu, Jianhe Hu   +38 more
doaj   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Biosafety challenges and the future landscape in Pakistan

Khyber Medical University Journal
Sepsis is a major threat to global health, as highlighted by the Global Burden of Disease Study, which recorded an estimated 48.9 million cases of sepsis globally, resulting in 11.0 million sepsis-related deaths, accounting for 19.7% of all global deaths
Akhtar Sherin
doaj   +1 more source

Water‐Enabled Ultralong Full‐Color Organic Phosphorescence in Hydrogen‐Bonded Frameworks for 4D Encryption and Bio‐Imaging

Advanced Science, EarlyView.
Water‐induced quenching challenges organic RTP materials, but a counter‐intuitive strategy employs HOF to encapsulate carbonyl guests, where water functions as a structural reinforcer. This achieves water‐enhanced ultralong RTP with full‐color emission (blue to deep red), overcoming intracellular quenching for high‐signal cellular imaging, alongside 4D
Pengcheng Wu, Zenggang Lin, Lu Yang, Weisheng Liu   +3 more
wiley   +1 more source

A truncated B-box zinc finger transcription factor confers drought sensitivity in modern cultivated tomatoes

Nature Communications
Enhancing drought tolerance in crops and understanding the underlying mechanisms have been subject of intense research. The precise function and molecular mechanisms of B-box zinc finger proteins (BBX) remain elusive.
Jinhua Li, Guo Ai, Yaling Wang, Yin Ding, Xiaomeng Hu, Yan Liang, Qingxia Yan, Ke Wu, Rong Huang, Chunrui Chen, Bo Ouyang, Xingguo Zhang, Yu Pan, Lang Wu, Zonglie Hong, Junhong Zhang   +15 more
doaj   +1 more source

EDUCAÇÃO PARA A BIOSSEGURANÇA EM LABORATÓRIOS DE ANÁLISES CLÍNICAS | Education for Biosafety in clinical analysis laboratories

Trabalho & Educação, 2018
Dissertation clipping aimed to investigate the knowledge of workers in clinical analysis laboratories about biosafety and to create a website to socialize information and contribute to health education. The research is of the cross-sectional and applied type and was carried out between the second half of 2015 and the first semester of 2016.
Rigo, Andressa Holsbach Berwanger, Fontana, Rosane Teresinha   +1 more
openaire   +2 more sources

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source