Results 91 to 100 of about 20,909 (242)

Fortifying Biosafety in Nigeria: Insights and Transformative Practices from the SNL-NIBSA Bio-risk Management Course

Babcock University Medical Journal
This study highlights the critical role of biosafety and biosecurity in scientific advancement and public health protection. It stresses responsible research conduct and risk mitigation.
Ishaku Leo Elisha, Ahmed Waleed Joyan
doaj   +1 more source

Cognitive load and performance of health care professionals in donning and doffing PPE before and after a simulation-based educational intervention and its implications during the COVID-19 pandemic for biosafety.

Le infezioni in medicina, 2020
The Personal Protective Equipment (PPE) is essential to avoid the COVID-19 spread to health care workers. Its use can be difficult, posing a high risk of contamination, mainly during doffing, then with the risk of becoming infected.We conducted a prospective before-and-after design that used clinical simulation as a research methodology in a clinical ...
Diego Andrés, Díaz-Guio, Alejandra, Ricardo-Zapata, Jeniffer, Ospina-Velez, Gabriel, Gómez-Candamil, Santiago, Mora-Martinez, Alfonso J, Rodriguez-Morales   +5 more
openaire   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Rapid and specific detection of Streptococcus suis serotype 2 using a RPA–PfAgo system coupled with fluorescence and lateral flow dipstick

Frontiers in Veterinary Science
ObjectiveTo develop and validate dual detection platforms integrating recombinase polymerase amplification (RPA) with Pyrococcus furiosus Argonaute (PfAgo) for the rapid and specific identification of Streptococcus suis serotype 2.MethodsThe conserved ...
Kexin Wang, Kexin Wang, Xujie Zhao, Xujie Zhao, Jingjing Li, Jingjing Li, Mingzhu Zhou, Mingzhu Zhou, Bingze Jiao, Bingze Jiao, Yilin Bai, Zhanwei Teng, Zhanwei Teng, Meinan Chang, Meinan Chang, Yueyu Bai, Jianhe Hu, Jianhe Hu, Ke Ding, Ke Ding, Xiaojing Xia, Xiaojing Xia   +21 more
doaj   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

AaeAP2a, a scorpion-derived antimicrobial peptide, combats carbapenem-resistant Acinetobacter baumannii via membrane disruption and triggered metabolic collapse

Frontiers in Microbiology
IntroductionCarbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant global health challenge owing to its high mortality rates and widespread antibiotic resistance.
Weiyu Luo, Weiyu Luo, Weiyu Luo, Weiyu Luo, Liuwei Zhang, Liuwei Zhang, Haolei Gao, Haolei Gao, Huiying Li, Huiying Li, Xiaofeng Li, Xiaofeng Li, Yuliang Wen, Yuliang Wen, Huarun Sun, Huarun Sun, Bolin Hang, Bolin Hang, Longfei Zhang, Longfei Zhang, Wei Zhang, Wei Zhang, Xuehan Liu, Xuehan Liu, Ruibiao Wang, Ruibiao Wang, Bo Wen, Bo Wen, Jiyuan Shen, Jiyuan Shen, Chunling Zhu, Chunling Zhu, Yueyu Bai, Lei Wang, Lei Wang, Ke Ding, Ke Ding, Jianhe Hu, Jianhe Hu   +38 more
doaj   +1 more source

EDUCAÇÃO PARA A BIOSSEGURANÇA EM LABORATÓRIOS DE ANÁLISES CLÍNICAS | Education for Biosafety in clinical analysis laboratories

Trabalho & Educação, 2018
Dissertation clipping aimed to investigate the knowledge of workers in clinical analysis laboratories about biosafety and to create a website to socialize information and contribute to health education. The research is of the cross-sectional and applied type and was carried out between the second half of 2015 and the first semester of 2016.
Rigo, Andressa Holsbach Berwanger, Fontana, Rosane Teresinha   +1 more
openaire   +2 more sources

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Necessity of introduction of educational disciplines on biosafety and bio-protection in educational programs of biologists in high educational institutions. Review [PDF]

Bulletin "Veterinary biotechnology", 2018
O. M. Andriychuk, H. V. Korotieieva, I. G. Budzanivska   +2 more
openaire   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source