Results 51 to 60 of about 119,313 (287)

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

Advanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula, Rosa M. Espinosa‐Marzal   +1 more
wiley   +1 more source

Label-free chemical imaging of cytochrome P450 activity by Raman microscopy

Communications Biology, 2022
Cytochrome P450 activity is assessed at the single-cell level using chemical imaging, Raman microscopy, which gives quantitative insights into effects of drug administration on cellular biochemistry.
Menglu Li, Yasunori Nawa, Seiichi Ishida, Yasunari Kanda, Satoshi Fujita, Katsumasa Fujita   +5 more
doaj   +1 more source

A Peptide Nucleic Acid‐Functionalized Heterojunction Thin Film Transistor as a Scalable and Reusable Platform for Label‐Free Detection of MicroRNA

Advanced Functional Materials, EarlyView.
A miniaturized, label‐free, and enzyme‐free biosensor (miR‐TFT) enables direct electrical detection of microRNA (miRNA) with single‐nucleotide specificity and a detection limit of 0.6 fM. Built on a tri‐channel In2O3/ZnO heterojunction and functionalized with bespoke peptide nucleic acid (PNA) probes, the device is robust, reusable, and compatible with
Wejdan S. Al Ghamdi, Jorge Romero Domínguez, Erol Hasan, Temur Maksudov, Thomas D. Anthopoulos, Dana Alsulaiman   +5 more
wiley   +1 more source

General (hetero)polyaryl amine synthesis via multicomponent cycloaromatization of amines

Nature Communications
(Hetero)polyaryl amines are extensively prevalent in pharmaceuticals, fine chemicals, and materials but the intricate and varied nature of their structures severely restricts their synthesis. Here, we present a selective multicomponent cycloaromatization
Lebin Su, Jianyu Dong, Yang Shen, Shimin Xie, Shaofeng Wu, Neng Pan, Feng Liu, Qian Shang, Fangfang Cai, Tian-Bing Ren, Lin Yuan, Shuang-Feng Yin, Li-Biao Han, Yongbo Zhou   +13 more
doaj   +1 more source

Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Nature Communications, 2020
Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and ...
Xiaoyi Fu, Guoliang Ke, Fangqi Peng, Xue Hu, Jiaqi Li, Yuyan Shi, Gezhi Kong, Xiao-Bing Zhang, Weihong Tan   +8 more
doaj   +1 more source

The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1

Cell & Bioscience, 2023
Background Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated.
Haojie Cheng, Jie Yuan, Chaozhu Pei, Min Ouyang, Huitong Bu, Yan Chen, Xiaoqin Huang, Zhenwang Zhang, Li Yu, Yongjun Tan   +9 more
doaj   +1 more source

BIOTEX-biosensing textiles for personalised healthcare management. [PDF]

, 2010
Textile-based sensors offer an unobtrusive method of continually monitoring physiological parameters during daily activities. Chemical analysis of body fluids, noninvasively, is a novel and exciting area of personalized wearable healthcare systems ...
Bini, Christina, Chartier, Isabelle, Chuzel, Cyril, Convert, Reynald, Costanzo, Daniele, Coyle, Shirley, De Rossi, Danilo, De-Moncuit, Henri, Di Francesco, Fabio, Diamond, Dermot, Giovanna Trivella, Maria, Lanier, Thierry, Lau, King-Tong, Luprano, Jean, Mourier, Veronique, Moyna, Niall, O'Gorman, Donal, Paradiso, Rita, Porchet, Jacques-André, Revol-Cavalier, Frederic, Ridofi, Andrea, Salvo, Pietro, Schoumacker, Sébastien, Taccini, Nicola   +23 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A tunable plasmonic refractive index sensor with nanoring-strip graphene arrays

, 2018
In this paper, a tunable plasmonic refractive index sensor with nanoring-strip graphene arrays is numerically investigated by the finite difference time domain (FDTD) method.
Cen, Chunlian, Chen, Xifang, Huang, Jing, Liang, Cuiping, Lin, Hang, Liu, Jiangwei, Tang, Yongjian, Xiao, Shuyuan, Ye, Xin, Yi, Yong, Yi, Zao   +10 more
core   +1 more source

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

Advanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source