Results 41 to 50 of about 201,023 (316)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Self-supervised representation learning using feature pyramid siamese networks for colorectal polyp detection

Scientific Reports, 2023
Colorectal cancer is a leading cause of cancer-related deaths globally. In recent years, the use of convolutional neural networks in computer-aided diagnosis (CAD) has facilitated simpler detection of early lesions like polyps during real-time ...
Tianyuan Gan, Ziyi Jin, Liangliang Yu, Xiao Liang, Hong Zhang, Xuesong Ye   +5 more
doaj   +1 more source

Acoustic biosensors [PDF]

Essays in Biochemistry, 2016
Resonant and acoustic wave devices have been researched for several decades for application in the gravimetric sensing of a variety of biological and chemical analytes. These devices operate by coupling the measurand (e.g. analyte adsorption) as a modulation in the physical properties of the acoustic wave (e.g.
Fogel, Ronen, Limson, Janice L, Seshia, Ashwin A   +2 more
openaire   +3 more sources

Novel graphene-based biosensor for early detection of Zika virus infection.

Biosensors & bioelectronics, 2018
We have developed a cost-effective and portable graphene-enabled biosensor to detect Zika virus with a highly specific immobilized monoclonal antibody.
S. Afsahi, Mitchell B. Lerner, J. Goldstein, Joo R. Lee, Xiaoling Tang, D. Bagarozzi, Deng Pan, Lauren E Locascio, Amy Walker, Francie E. Barron, B. Goldsmith   +10 more
semanticscholar   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Pathological In Vivo Analysis of Helicobacter DNA Infection in Stomach Cells Using Carbon Nanotube Microsensor

Microorganisms
The WHO has classified Helicobacter pylori as a group 1 carcinogen for stomach cancer since early 1994. However, despite the high prevalence of Helicobacter pylori infection, only about 3% of infected people eventually develop gastric cancer.Biomolecular
Kyung Lee, Sihyun Jun, Yeseul Oh, Seojun Lee, Ye Jun Oh, Keum Sook Kim, Suw Young Ly   +6 more
doaj   +1 more source

A Review of Recent Advances in Flexible Wearable Sensors for Wound Detection Based on Optical and Electrical Sensing

Biosensors, 2021
Chronic wounds that are difficult to heal can cause persistent physical pain and significant medical costs for millions of patients each year. However, traditional wound care methods based on passive bandages cannot accurately assess the wound and may ...
Xianyou Sun, Yanchi Zhang, Chiyu Ma, Qunchen Yuan, Xinyi Wang, Hao Wan, Ping Wang   +6 more
doaj   +1 more source

G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

Biosensors & bioelectronics, 2020
G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich DNA or RNA. The conformation and function of G-quadruplex are determined by a number of factors, including the number and polarity of nucleotide strands, the ...
Hui Xi, M. Juhas, Yang Zhang
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Synthesis and characterization of ZnS quantum dots and application for development of arginine biosensor

Sensing and Bio-Sensing Research, 2017
Arginine deiminase co-immobilized with ZnS QDs coupled micro-disk was applied for the sensing of arginine in real and spiked fruit samples. Intracellular arginine deiminase from Lactococcus lactis MTCC 460 was partially purified by ammonium sulphate ...
Neelam Verma, Ashish Kumar Singh, Nancy Saini   +2 more
doaj   +1 more source