Results 51 to 60 of about 201,023 (316)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Evaluating the efficacy and cardiotoxicity of EGFR-TKI AC0010 with a novel multifunctional biosensor

open access: yesMicrosystems & Nanoengineering, 2023
Non-small cell lung cancer (NSCLC) is a leading cause of cancer mortality worldwide. Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have dramatically improved the life expectancy of patients with NSCLC, concerns about ...
Deming Jiang   +11 more
doaj   +1 more source

An In Vitro HL-1 Cardiomyocyte-Based Olfactory Biosensor for Olfr558-Inhibited Efficiency Detection

open access: yesChemosensors, 2022
Some short-chain fatty acids with a pungent or unpleasant odor are important components of human body odor. These malodors severely threaten human health.
Qunchen Yuan   +9 more
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Salivary Cortisol Determination on Smartphone-Based Differential Pulse Voltammetry System

open access: yesSensors, 2020
Cortisol is commonly used as a significant biomarker of psychological or physical stress. With the accelerated pace of life, non-invasive cortisol detection at the point of care (POC) is in high demand for personal health monitoring.
Jingjing Liu   +10 more
doaj   +1 more source

Skin-like biosensor system via electrochemical channels for noninvasive blood glucose monitoring

open access: yesScience Advances, 2017
Electrochemical twin channels make glucose in vessels measurable by noninvasive ultrathin skin-like highly sensitive biosensors. Currently, noninvasive glucose monitoring is not widely appreciated because of its uncertain measurement accuracy, weak blood
Yihao Chen   +8 more
semanticscholar   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, Volume 28, Issue 11, 3 June 2026.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

Photoswitching Conduction in Framework Materials

open access: yesAdvanced Functional Materials, Volume 36, Issue 43, 29 May 2026.
This mini‐review summarizes recent advances in state‐of‐the‐art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses the various photoswitching conduction mechanisms and the strategies employed to enhance photoswitched conductivity.
Helmy Pacheco Hernandez   +4 more
wiley   +1 more source

Isolation and Characterization of Antiangiogenesis Compounds from the Fungus Associated with Using Zebrafish Assay

open access: yesNatural Product Communications, 2017
Three compouds, (+)-butyrolactone IV ( 1 ), butyrolactone I ( 2 ) and terrelactone A ( 3 ) were isolated from the fungus Aspergillus terreus associated with Apostichopus japonicus from the Yellow Sea in China; their structures were elucidated by spectral
Jun Qi   +8 more
doaj   +1 more source

Non-Covalent Functionalization of Carbon Nanotubes for Electrochemical Biosensor Development

open access: yesItalian National Conference on Sensors, 2019
Carbon nanotubes (CNTs) have been widely studied and used for the construction of electrochemical biosensors owing to their small size, cylindrical shape, large surface-to-volume ratio, high conductivity and good biocompatibility.
Yan Zhou, Yi Fang, R. Ramasamy
semanticscholar   +1 more source

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