Results 51 to 60 of about 109,704 (214)
Advanced Healthcare Materials, EarlyView.The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Plasma separation from whole blood is a necessary part of biomarker detection. Using conventional centrifugation undermines the goals of point‐of‐care devices and more automated biomarker analysis workflow. In this work, a high‐throughput hydrodynamic‐based microfluidic platform that separates plasma with admissible purity and yield is developed ...
Hesam Abouali +4 more
wiley +1 more source
Non‐Surgical, In‐Stent Membrane Bioelectronics for Long‐Term Intracranial Pressure Monitoring
Advanced Healthcare Materials, EarlyView.This image shows a sequence of long‐term intracranial pressure monitoring using non‐surgical, in‐stent membrane bioelectronics. Abstract Traditional intracranial pressure (ICP) monitoring methods, using intraventricular catheters, face significant limitations, including high invasiveness, discrete data, calibration complexities, and drift issues, which
Jimin Lee +9 more
wiley +1 more source
Topologically integrated photonic biosensor circuits [PDF]
arXivIntegrated nanophotonic biosensors offer a promising route toward future biomedical detection applications that may enable inexpensive, portable, and sensitive diagnosis of diseases with a small amount of biological samples for convenient early-stage screening of fatal diseases.
arxiv
Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy
Advanced Healthcare Materials, EarlyView.Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari +8 more
wiley +1 more source
Development of Bioorthogonally Degradable Tough Hydrogels Using Enamine N‐Oxide Based Crosslinkers
Advanced Materials, EarlyView.Inducibly degradable enamine N‐oxide crosslinkers are integrated into tough double network hydrogels, enabling rapid and bioorthogonal degradation by aqueous diboron solutions. These chemical reagent‐responsive biomaterials maintain structural integrity during use while enabling rapid degradation when needed, making them ideal for applications in ...
Thomas T. Kim +4 more
wiley +1 more source
Mass-sensing BioCD Protein Array towards Clinical Application: Prostate Specific Antigen Detection in Patient Sera [PDF]
arXiv, 2009 Mass-sensing biosensor arrays for protein detection require no fluorophores or enzyme labels. However, few mass biosensor protein arrays have demonstrated successful application in high background samples, such as serum. In this paper, we test the BioCD as a mass biosensor based on optical interferometry of antibodies covalently attached through Schiff-
arxiv
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
Detection limits in plasmonic whispering gallery mode biosensors [PDF]
arXiv, 2011 We analyze a whispering gallery mode biosensor with a metallic nanorod bound to its surface. It is found that a localized surface plasmon resonance in the nanorod can reduce the optical mode volume of the resonator by as much as four orders of magnitude via a local enhancement of the electric field, thus improving the detection sensitivity.
arxiv
Non-Electrode Biosensors in Clinical Biochemistry [PDF]
, 1985 Valerie M. Owen
openalex +1 more source