Results 101 to 110 of about 7,770 (204)

The Impact of the G8 Score on Survival Outcomes in Patients With Head and Neck Cancer Undergoing Concurrent Radiotherapy With Cetuximab due to Contraindications With Cisplatin

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Purpose Patients unable to receive cisplatin due to age, comorbidities, or reduced performance status are commonly treated with concurrent radiotherapy (RT) and cetuximab. This study evaluated the prognostic significance of the Geriatric 8 (G8) score and the Charlson Comorbidity Index (CCI) in predicting survival outcomes in this population ...
Esin Kiraz, Mete Gündoğ, Rıdvan Gönül, İrfan Kara, İmdat Yüce, Sedat Çağlı   +5 more
wiley   +1 more source

miR‐1246 as a Diagnostic, Prognostic, and Therapeutic Biomarker in Breast Cancer: A Narrative Review With Pharmacoeconomic Perspectives

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims MicroRNA‐1246 (miR‐1246) has emerged as an important regulatory molecule in breast cancer, with growing evidence supporting its role in diagnosis, prognosis, and therapeutic response. This review aims to evaluate the diagnostic, prognostic, and therapeutic significance of miR‐1246 in breast cancer and to assess its ...
Abrar Ghaith, Lulu Alsheikh Hussein
wiley   +1 more source

Budget impact analysis of the incorporating of biosimilars in a cancer institute of a philanthropic hospital

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde
Objective: Global healthcare costs continue to rise annually, and this is a major challenge given the scarce resources and growing prices of innovative drugs. An interesting alternative for reducing costs is the use of biosimilars.
Maria Luísa BRODT-LEMES, Diana Saiara BRUSCATO, Douglas Silva MADRUGA, Joice SMANIOTTO, Julia Roberta SAGGIORATO-LUBIAN, Letícia Tramontina DE-VILLA, Suhélen CAON, Thamyrys Bessa SILVA   +7 more
doaj   +1 more source

Anti‐PEG Antibodies From mRNA COVID‐19 Vaccines Affect In Vitro Measurements of Pegylated Drug Levels

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The recent adoption of mRNA‐based technology for vaccine development has led to widespread exposure to new vaccine components, such as polyethylene glycol (PEG), against which antibodies may be made. This study assesses the presence of anti‐PEG antibodies in human serum following SARS‐CoV‐2 vaccination, and if these antibodies could interfere ...
Elizaveta A. Svyatova, Zhuoming Liu, Robyn E. Becker, Jungeun M. Sung, Adetunji P. Fayomi, Jeffry A. Florian, James L. Weaver, Rodney Rouse, Kristina E. Howard   +8 more
wiley   +1 more source

Bridging the Pregnancy Knowledge Gap: A Real‐World Analysis of Medication Use and Drug–Drug Interaction Risk in Crohn's Disease and Multiple Sclerosis

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The exclusion of pregnant individuals from clinical trials has resulted in a significant medical knowledge gap for this population. Leveraging real‐world data (RWD) provides a critical window into the prevalence and use of medications during pregnancy.
Jacqueline Williams, Rucha Sane, Amita Joshi, Kit Wun Kathy Cheung, Bianca Vora   +4 more
wiley   +1 more source

Biosimilars and haemophilia [PDF]

Haemophilia, 2018
openaire   +2 more sources

Five‐Year Outcomes and Disease Trajectories in Moderate‐to‐Severe Ulcerative Colitis: A Korean Multicenter Inception Cohort

Journal of Gastroenterology and Hepatology, Volume 41, Issue 8, Page 2338-2348, August 2026.
ABSTRACT Background and Aim The incidence of ulcerative colitis (UC) has been increasing in Asia. Comprehensive data on the long‐term course of moderate‐to‐severe UC remain scarce. This study investigated the clinical outcomes and factors associated with a disabling disease course in Korean patients with moderate‐to‐severe UC.
Byong Duk Ye, Hyo Jong Kim, Dong Il Park, Young Sook Park, Kang‐Moon Lee, Jong Pil Im, Sung‐Ae Jung, Yoon Tae Jeen, Jae Myung Cha, Jae Hee Cheon, Sung Noh Hong, Youngdoe Kim, Jong Min Choi, YoungJa Lee, Chang Kyun Lee   +14 more
wiley   +1 more source

Biosimilars for Haematologic Malignancies: The Path to Sustainable Care

European Medical Journal Hematology, 2017
The main objectives of this symposium were to review the value of biosimilars in sustainable treatment for haematologic malignancies and to recognise the developmental differences between biosimilars and their reference products.
Paul Cornes, Arnold G. Vulto, Wojciech Jurczak   +2 more
doaj  

The approaches to the assessment of biosimilarity of biotechnological preparations: quality issues

Регуляторные исследования и экспертиза лекарственных средств, 2018
Due to expiration of patents for most highly demanded biotechnological preparations there is a tendency for the increase in the number of applications for marketing authorisation of biosimilar preparations (biosimilars).
A. N. Mironov, V. A. Merkulov, A. I. Lutseva, O. A. Vaganova, A. A. Bendryshev, T. A. Efremova, E. V. Kirichenko, S. V. Shvets, E. V. Ivanainen   +8 more
doaj  

The Current Use and Future Perspectives of Biosimilars in Pediatric Healthcare: A Narrative Review. [PDF]

Health Sci Rep
Ahmed Z, Maha TT, Nowsher S, Taslim W, Fatema-Tuz-Zohora, Sharmin S, Yasmin H.   +6 more
europepmc   +1 more source