Results 141 to 150 of about 420,917 (289)

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said   +13 more
wiley   +1 more source

Epidemiology as a Cornerstone of Brain Health: From Measuring Burden to Prevention, Equity and Policy

open access: yesBrain Health, EarlyView.
Epidemiology turns brain‐health evidence into action through six linked stages: characterise burden, map inequalities, identify determinants, evaluate interventions, assess implementation and value and translate evidence into policy, while maintaining data quality, equity, life‐course perspectives and stakeholder involvement.
Pierre‐Marie Preux   +1 more
wiley   +1 more source

Anatomical Communication in Surgical Informed Consent Documents: An Exploratory Application of the Anatomical Clarity Framework

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Surgical informed consent documents represent an important interface between anatomical knowledge and patient‐facing clinical information; however, no structured approach currently exists for evaluating how anatomy is represented and communicated within these materials.
Zeynep Nisa Karakoyun   +4 more
wiley   +1 more source

Experimental methods in chemical engineering: The scientific method versus engineering design methodology

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Engineering graduate students confuse the scientific method and problem solving when presenting their pre‐doctoral exams and theses: Science discourse adopts question and hypotheses to assert and establish a study's rationale, while it is problem and objectives in engineering design.
Gregory S. Patience   +4 more
wiley   +1 more source

Detecting communities when order and direction matter in social network analysis

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract A novel algorithm combining both node degree and edge betweenness (node degree+edge betweenness) is developed to highlight gradients in connectivity. It identifies communities within complex directed graphs. These are networks that are composed of actors who have ties that originate and end at themselves (self‐loops).
Benjamin Smith, Tyler Pittman, Wei Xu
wiley   +1 more source

DATA IN TABLES AND GRAPH Biostatistics

open access: yes
Four presentations in Biostatistics introduced by Dr. Basim Al-Samarrai covering the following topics: why Biostatistics is important to dentistry and medicine; organizing data in tables and graphs; statistical measures to describe data including its ...
BASIM AL-SAMARRAI (17933819)
core   +1 more source

Homophily‐adjusted social influence estimation

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Homophily and social influence are two key concepts of social network analysis. Distinguishing between these phenomena is difficult, and approaches to disambiguate the two have been primarily limited to longitudinal data analyses. In this study, we provide sufficient conditions for valid estimation of social influence through cross‐sectional ...
Hanh T.D. Pham, Daniel K. Sewell
wiley   +1 more source

102 CUBE: A Collaborative Undergraduate Biostatistics Experience to Bring Diversity and Awareness to the Field of Collaborative Biostatistics

open access: yes
OBJECTIVES/GOALS: Despite a steady rise of graduate degrees in biostatistics earned in the US, the percent from minorities remains low. This poster will describe the Collaborative Undergraduate Biostatistics Experience (CUBE), an 8-week program aimed to ...
Alicia Lozano   +5 more
core   +1 more source

Revisiting Fisher's n‐D statistical vision: From algebraic abstraction to modern visualization

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We revisit early foundational results in mathematical statistics derived by Ronald A. Fisher. They involve sampling distributions of statistics calculated from independent and identically distributed Normal observations, namely the root mean square deviation; the mean absolute deviation, conditional on already knowing the value of the root ...
James A. Hanley
wiley   +1 more source

Home - About - Disclaimer - Privacy