Results 151 to 160 of about 420,917 (289)

Irregular visits in longitudinal studies: Comparing inverse intensity of visit weighting and imputation in a causal analysis of antidepressant therapeutic treatment

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe   +2 more
wiley   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz   +5 more
wiley   +1 more source

Editorial: Methods for imaging and omics data science: advances, applications, and spatiotemporal innovations. [PDF]

open access: yesFront Genet
Mallick H   +7 more
europepmc   +1 more source

Biostatistics exams

open access: yes, 1976
DocumentoNote from the Civil Government Office of Porto about the reception of the postal notice regarding the Biostatistics exam to be taken by students of the Faculty of Medicine - University of Porto.Nota do Governo Civil do Porto acerca da recepção ...

core   +2 more sources

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit   +7 more
wiley   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy