Results 131 to 140 of about 1,464,623 (413)

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]

open access: yes, 2019
The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R   +6 more
core   +1 more source

Tocopherol and plastoquinone synthesis in spinach chloroplasts subfractions [PDF]

open access: yes, 1980
Subfractions isolated from intact purified spinach chloroplasts are able to prenylate the aromatic moiety of -tocopherol and plastoquinone-9 precursors. The biosynthesis of -tocopherol and plastoquinone-9 is a compartmentalized process.
Bickel   +21 more
core   +1 more source

Jasmonates: an update on biosynthesis, signal transduction and action in plant stress response, growth and development.

open access: yesAnnals of Botany, 2007
BACKGROUND Jasmonates are ubiquitously occurring lipid-derived compounds with signal functions in plant responses to abiotic and biotic stresses, as well as in plant growth and development.
C. Wasternack
semanticscholar   +1 more source

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

open access: yesFEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau   +3 more
wiley   +1 more source

Evolution of the genetic code. Why are there strong and weak letter doublets? The first gene, the first protein. Early (ancient) biosynthesis of protein [PDF]

open access: yesarXiv, 2008
The idea of the evolution of the genetic code from the CG to the CGUA alphabet has been developed further. The assumption of the originally triplet structure of the genetic code has been substantiated. The hypothesis of the emergence of stop codons at the early stage of the evolution of the genetic code has been additionally supported. The existence of
arxiv  

The effects of estrogen on targeted cancer therapy drugs

open access: yesPharmacological Research, 2022
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao   +4 more
doaj  

The TriForC database : a comprehensive up-to-date resource of plant triterpene biosynthesis [PDF]

open access: yes, 2018
Triterpenes constitute a large and important class of plant natural products with diverse structures and functions. Their biological roles range from membrane structural components over plant hormones to specialized plant defence compounds.
Bak, Soren   +8 more
core   +2 more sources

MYB20, MYB42, MYB43, and MYB85 Regulate Phenylalanine and Lignin Biosynthesis during Secondary Cell Wall Formation1[OPEN]

open access: yesPlant Physiology, 2019
MYB proteins regulate carbon flow into the phenylpropanoid pathway for lignin biosynthesis. Lignin is a phenylpropanoid-derived polymer that functions as a major component of cell walls in plant vascular tissues.
Pan Geng   +9 more
semanticscholar   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

open access: yesFEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

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