Results 141 to 150 of about 913,311 (370)

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Long-chain alkanol–alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma

Journal of Pharmaceutical Analysis, 2022
Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents (HDESs). These HDESs are liquid at room temperature and have low viscosity (
Anqi Huang, Wenwen Deng, Xiao Li, Qutong Zheng, Xuanxuan Wang, Yuxiu Xiao   +5 more
doaj  

Abstracting Asynchronous Multi-Valued Networks: An Initial Investigation [PDF]

arXiv, 2011
Multi-valued networks provide a simple yet expressive qualitative state based modelling approach for biological systems. In this paper we develop an abstraction theory for asynchronous multi-valued network models that allows the state space of a model to be reduced while preserving key properties of the model.
arxiv  

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

ON THE BIOSYNTHESIS OF CAROTENOIDS [PDF]

Journal of Biological Chemistry, 1954
C. O. Chichester, G. Mackinney, Patricia S. Wong   +2 more
openaire   +5 more sources

Analysing a Group of Homologous BAHD Enzymes Provides Insights into the Evolutionary Transition of Rosmarinic Acid Synthases from Hydroxycinnamoyl-CoA:Shikimate/Quinate Hydroxycinnamoyl Transferases

Plants
The interplay of various enzymes and compounds gives rise to the intricate secondary metabolic networks observed today. However, the current understanding of their formation and expansion remains limited. BAHD acyltransferases play important roles in the
Jiali Zhou, Xiaofang Zou, Zixin Deng, Lian Duan   +3 more
doaj   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Metastable Liquid–Liquid Phase Separation and Aging Lead to Strong Processing Path Dependence in Mini‐Spidroin Solutions

Advanced Functional Materials, Volume 35, Issue 15, April 10, 2025.
Biomolecular condensates have central functions in cells and are also observed during the assembly of biological materials such as silks. For a mini‐spidroin protein, the presence of long‐lived metastable or dynamically arrested intermediate states leads to complex pathways and difficulties in identifying equilibrium states. Constructing phase diagrams
Dmitrii Fedorov, Fred‐Eric Sammalisto, Adam L. Harmat, Martin Ahlberg, Salla Koskela, Mikko P. Haataja, Alberto Scacchi, Maria Sammalkorpi, Markus B. Linder   +8 more
wiley   +1 more source

Mycotoxins - Their Biosynthesis in Fungi: Biosynthesis of the Trichothecenes

Journal of Food Protection, 1979
The biosynthetic pathway as currently postulated for trichothecin, a model 12,13-epoxy-Δ9-trichothecene, involves the following sequence: 3 mevalonic acids → farnesyl pyrophosphate → trichodiene → trichodiol → 12,13-epoxytrichothec-9-ene → trichodermol → 12,13-epoxy,4β, 8a-dihydroxy-trichothec-9-ene → trichothecolone → trichothecin.
openaire   +3 more sources

Plant sesquiterpene lactones [PDF]

arXiv
Sesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the ecological significance of STLs, highlighting their roles in plant defense mechanisms against herbivory and as phytotoxins, alongside ...
arxiv