Results 131 to 140 of about 872,410 (312)

Molecular and structural studies on proteins involved in lipid biosynthesis in plants and bacteria [PDF]

open access: yes, 2002
Fatty acid synthesis in plants and most bacteria is catalysed by a type II, dissociable fatty acid synthetase, critically involving the participation of acyl-carrier protein (ACP) during synthesis and elongation reactions. This provides the substrate for
Simon, Josiah William
core  

Engineered AcrIIA5 for optogenetic control of CRISPR‐Cas9‐based genome editing

open access: yesmLife
The CRISPR‐Cas9 system has been proven to be a powerful tool for gene editing in living cells and shows great potential in genetic disease treatment. Anti‐CRISPR (Acr)‐based optogenetic tools could spatiotemporally regulate the activity of CRISPR‐Cas9 ...
Qi Chen   +5 more
doaj   +1 more source

Bacterial Cellulose‐Based Bilayer Passive Cooler for High‐Performance Radiative/Evaporative Cooling

open access: yesAdvanced Functional Materials, EarlyView.
A sustainable bilayer passive cooler based on bacterial cellulose integrates radiative and evaporative cooling for efficient zero‐energy temperature reduction. The scalable, low‐carbon material shows strong potential for food preservation, low‐temperature storage, and cold‐chain logistics.
Yibing Zhang   +6 more
wiley   +1 more source

Iron-sulphur protein catalysed [4+2] cycloadditions in natural product biosynthesis

open access: yesNature Communications
To the best of our knowledge, enzymes that catalyse intramolecular Diels-Alder ([4+2] cycloaddition) reactions are frequently reported in natural product biosynthesis; however, no native enzymes utilising Lewis acid catalysis have been reported ...
Yu Zheng   +10 more
doaj   +1 more source

Melanin's Role in Balancing Mechanical Strength and Reproductive Output in Environmentally Stressed Fungal Spores

open access: yesAdvanced Functional Materials, EarlyView.
Melanin content directly controls fungal spore mechanical properties, with pigmented spores achieving rupture forces two orders of magnitude higher than hyaline spores. Environmental stress drives this quantity‐quality tradeoff; stressed species invest energy in melanin‐reinforced, mechanically superior thick‐walled, super‐hydrophobic spores, while ...
Atul Agrawal, Steven E. Naleway
wiley   +1 more source

Investigation of phosphonate biosynthesis: I. Structure of dehydrophos II. Mechanism of hydroxyethylphosphonate dioxygenase [PDF]

open access: yes, 2010
Natural product phosphonates are used extensively in the clinic as antibacterials and in commercial agriculture as herbicides. In an effort to efficiently discover new natural product phosphonates, a multidisciplinary, collaborative program has been ...
Whitteck, John T.
core  

Advances in the Molecular Modification of Microbial ω-Transaminases for Asymmetric Synthesis of Bulky Chiral Amines

open access: yesMicroorganisms
ω-Transaminases are biocatalysts capable of asymmetrically synthesizing high-value chiral amines through the reductive amination of carbonyl compounds, and they are ubiquitously distributed across diverse microorganisms.
Xinxing Gao   +7 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

The biosynthesis of some bacterial and fungal polyketide metabolites [PDF]

open access: yes, 1994
Methylmalonyl-CoA is a key building block in the biosynthesis of propionate derived polyketide metabolites. There are several known metabolic sources of methylmalonyl-CoA, e.g. succinyl-CoA (citric acid cycle), valine and isoleudne.
Rogers, Sarah Victoria
core  

ON THE BIOSYNTHESIS OF CAROTENOIDS [PDF]

open access: yesJournal of Biological Chemistry, 1954
C O, Chichester, P S, Wong, G, Mackinney
openaire   +3 more sources

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