Results 271 to 280 of about 1,587,544 (388)
Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
Wheat DNA Methyltransferase TaMET1 Negatively Regulates Salicylic Acid Biosynthesis to Facilitate Powdery Mildew Susceptibility. [PDF]
Ge P, Chen W, Liu J, Wang X, Chang C.
europepmc +1 more source
Three types of enzymes complete the furanocoumarins core skeleton biosynthesis in Angelica sinensis
Kaixuan Wang +11 more
openalex +1 more source
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang +17 more
wiley +1 more source
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng +12 more
wiley +1 more source
<i>De novo</i> synthesis of L-2-aminobutyric acid in <i>Escherichia coli</i> based on multi-layered metabolic engineering strategies. [PDF]
Zhao Z +8 more
europepmc +1 more source
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source

