Results 271 to 280 of about 1,250,794 (338)

Metabolomic and physiological analysis of bud differentiation in dense apple <i>(Malus</i>×<i>domestica</i> Borkh.) orchards following thinning and reshaping. [PDF]

PeerJ
Yang Z, Guo T, Niu J, Yin X, Ma M.
europepmc   +1 more source

STUDIES OF DEOXYRIBONUCLEIC ACID BIOSYNTHESIS IN EMBRYONIC TISSUES WITH THYMIDINE-C14

, 1956
Morris Friedkin, Donald Tilson, DeWayne Roberts   +2 more
openalex   +1 more source

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source

Comparative Transcriptome Analysis of Walnuts (<i>Juglans regia</i> L.) in Response to Freezing Stress. [PDF]

Plants (Basel)
Chen L, Wang J, Zhang Q, Xu T, Ji Z, Hao H, Wang J, Shi G, Li J.   +8 more
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Transcriptome and metabolome profiling of the medicinal plant Dictamnus dasycarpus reveal key genes involved in quinoline alkaloids biosynthesis and limonoids biosynthesis. [PDF]

BMC Plant Biol
Mao J, Liu J, Hou Y, Fang X, Cheng X, Tian L, Ma Y, Yin H, Chen X.   +8 more
europepmc   +1 more source

The Biosynthesis of Squalene

, 1953
Robert Langdon, Konrad Bloch
openalex   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

Advanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi, Wen Tan, Haochun Jin, Sio I Chan, Wei Li, Si San Lei, Guozhen Cui, Yitao Wang, Dong‐Hua Yang, Zhangfeng Zhong   +9 more
wiley   +1 more source

Using BONCAT to dissect the proteome of <i>S. aureus</i> persisters. [PDF]

mSphere
George Matlalcuatzi EDC, Bakkum T, Thomas PS, Hacker S, Florea BI, Vriesendorp B, Rozen DE, van Kasteren SI.   +7 more
europepmc   +1 more source

Biosynthesis of fatty acids and cholesterol considered as chemical processes

, 1959
J. W. Cornforth
openalex   +1 more source