Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
The Mechanism of TT2-Type <i>MYB</i> Transcription Factor <i>JrMYB1L</i> in Anthocyanin Biosynthesis in 'Jinghong 1' Walnuts. [PDF]
Zhang S +8 more
europepmc +1 more source
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian +9 more
wiley +1 more source
Comparative transcriptome profiling reveals a role of 24-epibrassinolide in flavonoid biosynthesis in Gleditsia sinensis. [PDF]
Mu Z, Liu S, Xue Q, Yang J, Zhou H.
europepmc +1 more source
Post-transcriptional Regulation of Prostaglandin Biosynthesis
Fernando F. Blanco +3 more
openalex +1 more source
Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır +4 more
wiley +1 more source
Unraveling the Saline-Alkali-Tolerance Mystery of <i>Leymus chinensis</i> Nongjing-4: Insights from Integrated Transcriptome and Metabolome Analysis. [PDF]
Wang J +13 more
europepmc +1 more source
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
Integrative analysis of morphological, transcriptomic, and metabolomic approaches to uncover the function of flavonoids in the salt stress response of <i>Alhagi camelorum</i>. [PDF]
Tang G +7 more
europepmc +1 more source
Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji +12 more
wiley +1 more source

