Results 251 to 260 of about 356,384 (331)

Draft genome sequences of <i>Limosilactobacillus fermentum</i> BIL20 and BIL24, from Philippine fermented fish, feature biosynthetic gene clusters with diverse potential bioactivities. [PDF]

Microbiol Resour Announc
Veluz JT, Gloria PCT, Siringan MAT, Dogma IJ.   +3 more
europepmc   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules

FEMS Microbiology Reviews, 2017
Bethany K Okada, M. Seyedsayamdost
semanticscholar   +1 more source

Multi-site analysis of biosynthetic gene clusters from the periodontitis oral microbiome. [PDF]

J Med Microbiol
Koohi-Moghadam M, Watt RM, Leung WK.
europepmc   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

plantiSMASH 2.0: improvements to detection, annotation, and prioritization of plant biosynthetic gene clusters

Del Pup E, Owen C, Luo Z, Augustijn HE, Draisma A, Polturak G, Kautsar SA, Osbourn A, van der Hooft JJ, Medema MH.   +9 more
europepmc   +1 more source

An Improved Transformation-Associated Recombination Cloning Approach for Direct Capturing of Natural Product Biosynthetic Gene Clusters. [PDF]

Microb Biotechnol
Kurylenko O, Palusczak A, Luzhetskyy A, Rebets Y.   +3 more
europepmc   +1 more source

Biosynthetic Gene Cluster of Linaridin Peptides Contains Epimerase Gene

Biosynthetic Gene Cluster of Linaridin Peptides Contains Epimerase Gene
Salinipeptins belong to the type-A linaridin class of ribosomally synthesized and post-translationally modified peptides (RiPPs) comprising 22 amino acid residues with multiple D-amino acids. Although chirality of other type-A linaridins, such as grisemycin and cypemycin, has not been reported, the biosynthetic gene clusters of type-A linaridins have ...
openaire  

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Gene regulatory network resource aids in predicting trans-acting regulators of biosynthetic gene clusters in <i>Aspergillus fumigatus</i>. [PDF]

mBio
Seo H-w, Bok JW, Keller NP.
europepmc   +1 more source