Results 41 to 50 of about 1,526 (142)

Crioconservación de toxoplasma gondii

Biomédica: revista del Instituto Nacional de Salud, 1992
Toxoplasma gondii fue crioconservado en nitrógeno líquido usando como preservativo glicerol al 10% con el fin de mantener el protozoo por un largo período de tiempo. El descongelamiento de T. gondii se llevó a cabo, cuando los parásitos fueron requeridos
Sofía Duque Beltrán, María Mercedes Santacruz Chaves, Augusto Corredor Arjona   +2 more
doaj   +1 more source

Hit‐To‐Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira, Duarte Eduardo Pereira, Rafael Consolin Chelucci, Simone Michelan, Júlia Maria Fernandes Pituba, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Neide Maria Silva, Celso de Oliveira Rezende Júnior   +8 more
wiley   +1 more source

Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice

Journal of Oral Pathology &Medicine, Volume 55, Issue 6, Page 705-717, July 2026.
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno, Igor de Campos Fontes, Leticia Cristine Cardoso dos Santos, Victor Prokop Gonçalves Campos, Iury Berckmann Freitas Gomes, Derek William Gilroy, Silvia Passos Andrade, Paula Peixoto Campos   +7 more
wiley   +1 more source

Regeneração do nervo infra-orbital por neurotmese intrabucal

Revista da Faculdade de Odontologia de Porto Alegre, 1998
Os nervos periféricos não estão livres de sofrer alterações de qualquer tipo, que se traduzem em uma perda de função, a condução nervosa, causando alterações sensitivas e motoras que anulam funcionalmente órgãos importantes, tais como os que o ...
Ricardo Eugenio Varela Ayres de Melo, Manoel Sant'Ana Filho   +1 more
doaj   +7 more sources

Malária experimental: contaminação de cepas e animais de biotério por eperythrozoon coccoides

Revista do Instituto de Medicina Tropical de São Paulo, 1986
Neste artigo descrevemos a contaminação acidental de uma cepa de malária de roedor (Plasmodium berghei) por um hemoparasita (Eperythrozoon coccoides), levando a alterações importantes no comportamento da malária experimental.
Heitor Franco de Andrade Jr., Márcia Dalastra Laurenti, Hiro Goto, Maria Irma Seixas Duarte, Carlos Eduardo Pereira Corbett   +4 more
doaj   +1 more source

Disruption of ATP Synthase Spatiotemporal Organization, Ca2+ Dynamics, and Contractile Function in Senescent Cardiomyocytes

Aging Cell, Volume 25, Issue 2, February 2026.
Enhanced ATP hydrolysis, ΔΨm flickering, and destabilized ATP synthase dimers collectively reduce ATP availability in senescent cardiomyocytes. This energy deficit is associated with disrupted Ca2⁺ dynamics and contractility. ABSTRACT Heart disease is the leading cause of death in the elderly population.
Silke Morris, Nico Marx, Gonzalo Barrientos, Isidora Molina‐Riquelme, Frank Schmelter, Hugo E. Verdejo, Stefan Peischard, Guiscard Seebohm, Verónica Eisner, Karin B. Busch   +9 more
wiley   +1 more source

AAV‐Driven miR‐146a Promotes Neurite Outgrowth and Axonal Regeneration in Cortical Neurons

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
In the adult central nervous system (CNS), neuronal regeneration after injury is limited, resulting in poor functional recovery. MicroRNAs (miRNAs), a class of small noncoding RNAs that control gene expression, have gained attention as potential therapeutic agents, although their contribution to CNS repair remains insufficiently understood.
V. U. S. Matos, R. A. Almeida, C. G. Ferreira, M. T. R. Alves, M. P. Braga, M. C. Silva, T. F. da Silva, P. P. G. Guimarães, F. M. Soriani, P. Caramelli, M. R. Costa, U. Michel, V. T. Ribas   +12 more
wiley   +1 more source

Prevalência de Helicobacter em cães oriundos do biotério central da Universidade Estadual de São Paulo (UNESP)-Botucatu Prevalence of Helicobacter in canines from animal colony of the State University of Sao Paulo (UNESP)-Botucatu

Acta Cirúrgica Brasileira, 2004
OBJETIVO: Investigar a incidência de Helicobacter sp em cães oriundos do biotério central da UNESP. MÉTODOS: Utilizamos 109 cães oriundos do Biotério Central da UNESP Campus de Botucatu verificando a presença do Helicobacter sp através do exame de ...
Maria Lúcia de Souza, Shoiti Kobayasi, Maria Aparecida Marchesan Rodrigues, Rogério Saad-Hossne, Luiz Eduardo Naresse   +4 more
doaj   +1 more source

Cortisol influence on testicular testosterone secretion in domestic cat: An in vitro study Ação do cortisol sobre a secreção de testosterona em testículos de gato doméstico: um estudo in vitro

Pesquisa Veterinária Brasileira, 2010
The aim of the present experiment was to investigate the effect of corticosteroids (exogen) on in vitro testosterone secretion after stress by transportation (40 minutes).
Gelson Genaro, Celso R Franci
doaj   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira, Isabella Silva Cassimiro, Francyelle Borges Rosa de Moura, Tais de Campos Lima, Danielle Reis Napolitano, Eric Umehara, João Henrique Ghilardi Lago, Fernanda de Assis Araújo   +7 more
wiley   +1 more source