Results 91 to 100 of about 2,340,402 (343)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
THE BUTCHER THE BAKER THE PHARMACEUTICAL MAKER: WHY THE AGRICULTURAL BIOTECH INDUSTRY MAY DIFFER FROM THE GENERAL BIOTECH INDUSTRY [PDF]
This paper explores the apparent anomaly in the patenting strategies found in the agricultural biotechnology industry, when it is compared to the literature's view of the patenting strategies in the general biotechnology industry and in the ...
Dierker, Daniel A., Phillips, Peter W.B.
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Project-Based Learning to Promote Effective Learning in Biotechnology Courses [PDF]
, 2012 Farahnaz Movahedzadeh +3 more
openalex +1 more source
THE ECONOMICS OF BIOSAFETY: IMPLICATIONS FOR BIOTECHNOLOGY IN DEVELOPING COUNTRIES [PDF]
There is a growing body of literature on the safe use of biotechnology and the need for an international biosafety protocol and national regulations to facilitate the safe development and transfer of biotechnology. Most of these studies, however, address
Maredia, Mywish K.
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Bioinformatics in microbial biotechnology – a mini review [PDF]
, 2005 Arvind K. Bansal
openalex +1 more source
PUBLIC PERCEPTIONS OF BIOTECHNOLOGY AND ACCEPTANCE OF GENETICALLY MODIFIED FOOD [PDF]
Public debate on biotechnology is embroiled in controversy over the risks and benefits associated with this emerging technology. Using data from a national survey, this study analyzes public acceptance of biotechnology in food production.
Adelaja, Adesoji O. +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Durable vesicles for reconstitution of membrane proteins in biotechnology [PDF]
, 2017 Paul A. Beales +3 more
openalex +1 more source