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Strategic planning for the development of industrial biotechnological enterprises
The role of biotechnology and biotechnology products in the development of the Russian economy as a whole was determined. A comprehensive model of the interconnection between the life cycles of biotechnologies and biotechnological products, as well as ...
A. S. Glazkova, V. A. Epifanov
doaj
BIOTECHNOLOGY REVOLUTION AND POTENTIAL MILITARY APPLICATIONS
In the 21st century, biotechnology is no doubt one of the fields in science and technology with the most developmental potential. Modern-day biotechnology is a multidisciplinary field where its utility has grown from traditional uses like agriculture and
N Egbe
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Biotechnology of coconut (Cocos nucifera L.) is a relatively recent area compared to similar work in other crops. It started as tissue culture in the eighties, which led to the development of molecular markers in late nineties with the use of RAPDs ...
V A Parthasarathy +2 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Practicing environmental biotechnology
Environmental biotechnology involves ″managing microbial communities to provide services to society″.Its success comes from partnering with prokaryotic microorganisms,whose wideranging metabolic capabilities can be harnessed to destroy pollutants and to
Bruce E.Rittmann
doaj +1 more source
BIOTECHNOLOGY AND THE HUMAN GOOD
Preface -- Acknowledgments -- 1. The rapidly changing world of biotechnology -- 2. Humanity and the technological narrative -- 3. Biotechnology and competing worldviews -- 4. Biotechnology and human dignity -- 5.
Mitchell, C. Ben; Pellegrino, Edmund D.; Elshtain, Jean Bethke; Kilner, John F.; Rae, Scott B.
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Perkembangan Bioteknologi di Indonesia
Bioteknologi telah berkembang di Indonesia sejak lama namun cenderung lambat dikarenakan oleh beberapa faktor. Faktor pertama adalah minimnya dana penelitian dalam bidang bioteknologi.
Ummi Wasilah +2 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

