Results 71 to 80 of about 1,708,201 (311)
NABC statement 2000 on agricultural biotechnology: promise, process, regulation, and dialogue
, 1999 National Agricultural Biotechnology ...
National Agricultural Biotechnology Council [NABC]
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Strategic planning for the development of industrial biotechnological enterprises
Путеводитель предпринимателя, 2020 The role of biotechnology and biotechnology products in the development of the Russian economy as a whole was determined. A comprehensive model of the interconnection between the life cycles of biotechnologies and biotechnological products, as well as ...
A. S. Glazkova, V. A. Epifanov
doaj
BIOTECHNOLOGY REVOLUTION AND POTENTIAL MILITARY APPLICATIONS
Academy Journal of Science and Engineering, 2022 In the 21st century, biotechnology is no doubt one of the fields in science and technology with the most developmental potential. Modern-day biotechnology is a multidisciplinary field where its utility has grown from traditional uses like agriculture and
N Egbe
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Czech research in veterinary medicine
Veterinární Medicína, 2001 The task of applied research is not only to acquire new knowledge, through which it contributes to the development of economy, to the consumer protection or to the training of qualified experts.
K. Hruška
doaj +1 more source