Results 91 to 100 of about 1,708,201 (311)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Biotechnology

open access: yes, 2003
review of Our Posthuman Future: Consequences of the Biotechnology Revolution, by Francis ...
Abrams, Fredrick R.
core  

PERSPEKTIF MENYIAPKAN LULUSAN YANG ADAPTIF UNTUK MENDUKUNG KETERAMPILAN ABAD 21 DALAM PERKULIAHAN BIOTEKNOLOGI

open access: yesFlorea: Jurnal Biologi dan Pembelajarannya, 2014
The ability to cope with environmental stresses and to survive is adaptive. This is due to the changes that occur very rapidly due to the need to adapt according to the demands at the time. Improving the quality of learning is dynamic so that the quality
Hasan Subekti
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Biotechnology and the Law

open access: yes, 2007
Preface -- About the editors -- About the contributors -- Ch. I. Introduction to biotechnology and the law / Robert F. Copple -- Ch. II. Managing innovation: patent basics for biotechnology counsel / Michael H. Brodowski, Thomas A.
Cooper, Iver P.
core  

PENGEMBANGAN BAHAN AJAR BERBASIS PENELITIAN KARAKTERISASI PROTEIN MEMBRAN SPERMA PADA MATAKULIAH BIOTEKNOLOGI

open access: yesFlorea: Jurnal Biologi dan Pembelajarannya, 2015
The purpose of the research and development is to produce teaching materials such as textbooks supporting course in Biotechnology research based on the characterization of the sperm membrane proteins for students who take a course in Biotechnology.
Ika Oktaviana   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

UNCOVERING FACTORS INFLUENCING PUBLIC PERCEPTIONS OF FOOD BIOTECHNOLOGY [PDF]

open access: yes
Significant divergence exists in public opinions about biotechnology. Although there is broad support for plant biotechnology for health benefits, opinions differ on the issue of animal genetics for pure economic benefits.
Onyango, Benjamin M.   +4 more
core  

Böcek Virüslerinin Biyoteknolojik Önemi

open access: yesJournal of Agricultural Sciences, 2008
Böcek virüsleri, böcekleri enfekte ederek, onların hastalanmaları veya ölmelerine neden olan biyolojik etmenlerdir. Son yıllarda, bu virüsler modern biyoteknoloji uygulamalarında önemli ölçüde ilgi uyandırmaktadır.
Remziye Nalçacıoğlu   +2 more
doaj   +1 more source

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