Results 81 to 90 of about 1,708,201 (311)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Biotechnology and Bioengineering [PDF]
, 2019 Biotechnology and Bioengineering presents the most up-to-date research on biobased technologies. It is designed to help scientists and researchers deepen their knowledge in this critical knowledge field.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
BIOTECHNOLOGY AND THE HUMAN GOOD
, 2007 Preface -- Acknowledgments -- 1. The rapidly changing world of biotechnology -- 2. Humanity and the technological narrative -- 3. Biotechnology and competing worldviews -- 4. Biotechnology and human dignity -- 5.
Mitchell, C. Ben; Pellegrino, Edmund D.; Elshtain, Jean Bethke; Kilner, John F.; Rae, Scott B.
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Does New Zealand have an innovation system for biotechnology? [PDF]
, 2002 While there is a large and growing international literature on economic aspects of biotechnology innovation (e.g. work by Carlsson, McKelvey, Orsenigo, Zucker and Darby) these studies concentrate on the United States and Europe.
Marsh, Dan
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, 2007 Biotechnology is at the intersection of science and ethics. Technological developments are shaped by an ethical vision, which in turn is shaped by available technology. Much in biotechnology can be celebrated for how it benefits humanity.
O'Mathúna, Dónal P
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The transaction costs in biotechnology [PDF]
This paper aims to relate the principles of Ronald Coase Theorem with negative impacts of biotechnology, taking cases of specific research groups and medium-sized companies in biotechnology.
Estrada, Fernando, Diaz, Natalia
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