Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
THE BUTCHER THE BAKER THE PHARMACEUTICAL MAKER: WHY THE AGRICULTURAL BIOTECH INDUSTRY MAY DIFFER FROM THE GENERAL BIOTECH INDUSTRY [PDF]
This paper explores the apparent anomaly in the patenting strategies found in the agricultural biotechnology industry, when it is compared to the literature's view of the patenting strategies in the general biotechnology industry and in the ...
Dierker, Daniel A., Phillips, Peter W.B.
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
CONSUMER ACCEPTANCE OF FOOD BIOTECHNOLOGY: WILLINGNESS TO BUY GENETICALLY MODIFIED FOOD PRODUCTS [PDF]
Biotechnology is often viewed as the defining technology for the future of food and agriculture with the potential to deliver a wide range of economic and health benefits.
Adelaja, Adesoji O. +4 more
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Technology Vs Nature: Human Error in Dealing with Nature in Crichton\u27s Jurassic Park [PDF]
, 2000 Witnessing the euphoria of the era of biotechnology in the late twentieth century, Crichton exposes the theme of biotechnology in his works. In Jurassic Park, he voices his concern about the impact of the use of biotechnology to preserve nature and its ...
Prasasti, S. (Sarah) +1 more
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
PUBLIC PERCEPTIONS OF BIOTECHNOLOGY AND ACCEPTANCE OF GENETICALLY MODIFIED FOOD [PDF]
Public debate on biotechnology is embroiled in controversy over the risks and benefits associated with this emerging technology. Using data from a national survey, this study analyzes public acceptance of biotechnology in food production.
Adelaja, Adesoji O. +4 more
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A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
The current biotechnology outlook in Malaysia [PDF]
Blessed with extremely rich biodiversity, Malaysia is all geared up to explore new high technology to utilize the advantage it possesses whilst to protect its environment.
Khairiah Salwa MOKHTAR, Ravi MAHALINGAM
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University Scholar Series: Scott Shaffer [PDF]
, 2013 A New Form Of Biotechnology: Novel Data Logging Devices Reveal Secrets About The Lives Of Marine Animals On September 25, 2013, Dr. Scott Shaffer gave a talk titled “A New Form Of Biotechnology: Novel Data Logging Devices Reveal Secrets About The Lives ...
Shaffer, Scott
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