Results 101 to 110 of about 2,525,099 (341)

Space and biotechnology: An industry profile [PDF]

open access: yes
The results of a study conducted by the Center for Space and Advanced Technology (CSAT) for NASA-JSC are presented. The objectives were to determine the interests and attitudes of the U.S.
Johnston, Richard S.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

How a fungus shapes biotechnology: 100 years of Aspergillus niger research

open access: yesFungal Biology and Biotechnology, 2018
In 1917, a food chemist named James Currie made a promising discovery: any strain of the filamentous mould Aspergillus niger would produce high concentrations of citric acid when grown in sugar medium.
T. Cairns, Corrado Nai, V. Meyer
semanticscholar   +1 more source

The magic of the century we live in. The supremacy of three bio factors and their impact on firms trading [PDF]

open access: yes
Technology has come to be appreciated as key to the competitiveness of micro and macroeconomic level. Technological environment affecting business firms by increasing trade efficiency in making services and quality of services. Usually there should be no
ENEA Constanta   +1 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The transaction costs in biotechnology [PDF]

open access: yes
This paper aims to relate the principles of Ronald Coase Theorem with negative impacts of biotechnology, taking cases of specific research groups and medium-sized companies in biotechnology.
Diaz, Natalia, Estrada, Fernando
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

PUBLIC PERCEPTIONS OF BIOTECHNOLOGY AND ACCEPTANCE OF GENETICALLY MODIFIED FOOD [PDF]

open access: yes
Public debate on biotechnology is embroiled in controversy over the risks and benefits associated with this emerging technology. Using data from a national survey, this study analyzes public acceptance of biotechnology in food production.
Adelaja, Adesoji O.   +4 more
core   +1 more source

Technology Vs Nature: Human Error in Dealing with Nature in Crichton\u27s Jurassic Park [PDF]

open access: yes, 2000
Witnessing the euphoria of the era of biotechnology in the late twentieth century, Crichton exposes the theme of biotechnology in his works. In Jurassic Park, he voices his concern about the impact of the use of biotechnology to preserve nature and its ...
Prasasti, S. (Sarah)   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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