Results 51 to 60 of about 2,102,932 (360)
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Impact of Global Patent and Regulatory Reform on Patent Strategies for Biotechnology [PDF]
I come to you this morning not as an intellectual property lawyer but as a former general counsel of biotechnology and pharmaceutical related companies, as an attorney with significant exposure to intellectual property issues and as one who has seen ...
Napoleon, Vincent J.
core +3 more sources
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker+14 more
wiley +1 more source
Genetic modification techniques are now well established in agriculture (Brooks and Barfoot, 2009; James, 2010). The same extensive commercial application of genetic modification has not been seen in horticulture and floriculture, with the exception of ...
S.F. Chandler
doaj +1 more source
Functional characterisation of a nicotinic acetylcholine receptor alpha subunit from the brown dog tick, Rhipicephalus sanguineus [PDF]
Open Access funded by Biotechnology and Biological Sciences Research Council Under a Creative Commons license This work was supported by a Biotechnology and Biological Sciences Research Council (UK) Industrial CASE studentship award (BBSSM200411428) to K.
Alan S. Bowman+72 more
core +3 more sources
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Quantum technologies leverage the laws of quantum physics to achieve performance advantages in applications ranging from computing to communications and sensing. They have been proposed to have a range of applications in biological science. This includes better microscopes and biosensors, improved simulations of molecular processes, and new ...
arxiv
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler+12 more
wiley +1 more source