Results 71 to 80 of about 2,102,932 (360)

Fostering innovation in a small open economy: The case of the New Zealand biotechnology sector [PDF]

open access: yes, 2000
The New Zealand Biotechnology sector is worthy of study for several reasons. While there is a large and growing international literature on economic aspects of biotechnology innovation these studies concentrate on the United States and Europe.
Marsh, Dan
core   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

Are Biotechnology Startups Different? [PDF]

open access: yesarXiv, 2018
In the domain of technology startups, biotechnology has often been considered as specific. Their unique technology content, the type of founders and managers they have, the amount of venture capital they raise, the time it takes them to reach an exit as well as the technology clusters they belong to are seen as such unique features.
arxiv  

The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas [PDF]

open access: yes, 2017
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria and archaea cells. A heritable, molecular memory is generated of phage, plasmids, or other mobile genetic elements that attempt to attack the cell.
arxiv   +1 more source

Biotechnology's wheel of knowledge [PDF]

open access: yes, 2006
Article with results of study carried out to raise awareness of the role of biotechnology in the New Zealand curriculum. The findings highlighted that biotechnology learning needs to be situated in real life contexts that are relevant to the ...
Buntting, Catherine Michelle   +1 more
core   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

The Impact of Innovative Teaching Approaches on Biotechnology Knowledge and Laboratory Experiences of Science Teachers

open access: yesEducation Sciences, 2018
The current study presents an evaluation of the laboratory instructional tasks prepared based on innovative teaching approaches (research-inquiry, problem solving, project, argumentation and web-based interdisciplinary learning approaches) designed to ...
Tugce Yagmur Orhan, Nurettin Sahin
doaj   +1 more source

Whose intentions? What consequences? Interrogating “Intended Consequences” for conservation with environmental biotechnology

open access: yesConservation Science and Practice, 2021
Novel genetic interventions may offer innovative solutions to environmental conservation challenges, but they also represent new kinds of risks and concerns for diverse publics.
S. Kathleen Barnhill‐Dilling   +1 more
doaj   +1 more source

Novel Techniques and Their Applications to Health Foods, Agricultural and Medical Biotechnology: Functional Genomics and Basic Epigenetic Controls in Plant and Animal Cells [PDF]

open access: yes, 2004
Selected applications of novel techniques for analyzing Health Food formulations, as well as for advanced investigations in Agricultural and Medical Biotechnology aimed at defining the multiple connections between functional genomics and epigenomic ...
Baianu, I.C.   +3 more
core  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

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