Results 141 to 150 of about 2,536 (255)

Targeting vaginal dysbiosis: prospects for the application of live biotherapeutics products. [PDF]

Front Microbiol
Zhang Q, Zhao X, Chen Z, Chen R, Lin X, Zhang L, Li K, Wang M, Liu Y, Zhou H, Liao Q.   +10 more
europepmc   +1 more source

Advances in treating bacterial vaginosis: recognizing sexual transmission and pipeline of therapies. [PDF]

Curr Opin Infect Dis
Kim ES, Waltmann A, Duncan JA, Hood-Pishchany I.   +3 more
europepmc   +1 more source

Systemic Delivery of Functional Proteins Into Plants Using an Engineered Membrane Translocation Domain

Plant Biotechnology Journal, EarlyView.
ABSTRACT Protein‐based biopesticides and biostimulants are critical for the future of sustainable agriculture, yet their utility is severely limited by inefficient delivery into plant cells. Traditional cell‐penetrating peptides enable protein uptake but lack the efficiency, systemic activity and scalability required for crop production.
Jiyang Wang, Preeti Patel, Prabhat Bhat, Cailin Hu, Cameron Storch, Brendan Harty, Maria Bellizzi, Colton Jordan, Devin Good, Venkat Gopalan, Jonathan Michael Jacobs, Dehua Pei, Guo‐Liang Wang   +12 more
wiley   +1 more source

Signed, sealed, delivered: a generalizable model for living biotherapeutic dosing and metabolism. [PDF]

NPJ Syst Biol Appl
DeVito VL, Karamched BR.
europepmc   +1 more source

Shaping the future of probiotics, live biotherapeutic products, and fecal microbiota transplantation: 30 scientific recommendations from the CHINAGUT Conference. [PDF]

Imeta
Wang W, Bu N, Cao H, Chen N, Chen W, Cheng L, Cui B, Dai L, Gao H, Guo M, He X, Hu J, Jiang C, Jiang X, Li J, Li P, Li W, Liao W, Liu H, Liu J, Liu L, Liu S, Liu X, Lv M, Ma Y, Man C, Pi Z, Ren Q, Sang L, Sun Z, Suo H, Tan Y, Tao W, Wang G, Wang J, Wang L, Wang X, Wang X, Wang Y, Wu K, Wu R, Wu Z, Xiao X, Xiang B, Yang S, Yi H, Yu H, Yu J, Zeng Y, Zhai H, Zhai Q, Zhang C, Zhang G, Zhang J, Zhang W, Zhao F, Zhao L, Zhou H, Zhu L, Lan C, Zhang H, Zhu S, Zhang F.   +62 more
europepmc   +1 more source

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He, Qiuhong Ouyang, Xinglv Chen, Qian Zhong, Xunhuan Song, Yujie Sun, Bingran Yu, Meng Qin   +7 more
wiley   +1 more source

Recent Advances in Hydrogels for Tissue Engineering and Biomedical Therapeutics. [PDF]

Gels
Lee HJ.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, Volume 16, Issue 5, Page 1030-1043, May 2026.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Targeting the gut microbiome in inflammatory bowel disease: from concept to clinical reality. [PDF]

Intest Res
Rolhion N, Sokol H.
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, Volume 13, Issue 5, Page 958-971, May 2026.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source