Results 121 to 130 of about 277,237 (293)

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang   +10 more
wiley   +1 more source

BIOTIN AND THE SYNTHESIS OF ASPARTIC ACID BY MICROORGANISMS

open access: hybrid, 1947
J. L. Stokes   +2 more
openalex   +1 more source

Observations on Biotin

open access: yesJournal of Investigative Dermatology, 1951
Frederick Kalz, V.A. Kral, R Roy Forsey
openaire   +3 more sources

Recent Advances in mRNA Delivery Systems for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang   +9 more
wiley   +1 more source

THE PREPARATION OF C14-LABELED BIOTIN AND A STUDY OF ITS STABILITY DURING CARBON DIOXIDE FIXATION

open access: hybrid, 1949
Donald B. Melville   +2 more
openalex   +1 more source

Biotin

open access: yesAdvances in Nutrition
Cydne A Perry, Tammy A Butterick
openaire   +2 more sources

Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang   +13 more
wiley   +1 more source

METABOLIC FUNCTIONS OF BIOTIN

open access: hybrid, 1949
Patricia MacLeod   +3 more
openalex   +1 more source

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma   +14 more
wiley   +1 more source

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