Results 121 to 130 of about 338,983 (344)

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Near equilibrium unbinding of streptavidin/biotin using single molecule acoustic force spectroscopy [PDF]

Yogesh Saravanan, Lorenzo Villanueva, Christian Lévêque, Mauro Modesti, Oussama El Far, Claire Valotteau, Félix Rico   +6 more
openalex   +1 more source

Simultaneous detection of different mRNA sequences coding for neuropeptide hormones by double in situ hybridization using FITC- and biotin-labeled oligonucleotides. [PDF]

, 1990
R.W. Dirks, R P van Gijlswijk, Richard H. Tullis, A.B. Smit, Jan van Minnen, M. van der Ploeg, Anton K. Raap   +6 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Advances in Hydrophilic Drug Delivery: Encapsulation of Biotin in Alginate Microparticles

Pharmaceutics
Background: The encapsulation of hydrophilic drugs within microparticles has gained significant interest in drug delivery systems due to their potential to improve stability, bioavailability, and controlled release of therapeutic agents.
Iria Naveira-Souto, Elisabet Rosell-Vives, Eloy Pena-Rodríguez, Francisco Fernandez-Campos, Maria Lajarin-Reinares   +4 more
doaj   +1 more source

Wolbachia supplement biotin and riboflavin to enhance reproduction in planthoppers

The ISME Journal, 2019
Jiafei Ju, Xiaoli Bing, Dian‐Shu Zhao, Yan-Fei Guo, Z. Xi, A. Hoffmann, KAI-JUN Zhang, Hai-Jian Huang, Jun-Tao Gong, Xu Zhang, X. Hong   +10 more
semanticscholar   +1 more source

Ask a Pathologist: Biotin Interference. A Cause for Concern?

, 2018
Jared Coberly
openalex   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Effects of additional dietary levels of folic acid, biotin, vitamin K, and selenium on egg production, fertility, hatchability, early and late embryonic mortality in White Pekin duck breeders

, 1984
Simon Piedade DeSouza
openalex   +1 more source