Results 141 to 150 of about 488,335 (365)

Antifouling PEG Coatings by Thiol‐Acrylate Conjugate Addition Reactions for Generation of Protein Patterns via Photobleaching‐Induced Protein Binding (PiPB) BioBitmaps Using Maskless Projection Lithography

open access: yesAdvanced Materials Interfaces, EarlyView.
Homo‐bifunctional PEG, acrylate‐PEG‐acrylate (PEGDA), coatings are prepared on glass and glass‐type surfaces using solvent‐free thiol‐acrylate conjugate addition reactions at room temperature. The prepared PEGDA coatings are stable, antifouling, and provide feature terminal acrylates that can act as free radical acceptors for photobleaching‐induced ...
Ali Usama   +11 more
wiley   +1 more source

Dual-topology insertion of a dual-topology membrane protein. [PDF]

open access: yes, 2015
Some membrane transporters are dual-topology dimers in which the subunits have inverted transmembrane topology. How a cell manages to generate equal populations of two opposite topologies from the same polypeptide chain remains unclear.
Bowie, James U   +2 more
core  

Modification and Patterning of Thiolate‐Anchored Self‐Assembled Monolayers with UV Light

open access: yesAdvanced Materials Interfaces, EarlyView.
This paper reviews the relevant work regarding the modification and patterning of thiolate‐anchored self‐assembled monolayers with UV light. Performed alone or in combination with a subsequent exchange reaction, introducing specific molecular substituents, this approach enables the preparation of functional binary SAMs and the creation of complex ...
Michael Zharnikov, Andreas Terfort
wiley   +1 more source

Population pharmacokinetics of exogenous biotin and the relationship between biotin serum levels and in vitro immunoassay interference

open access: yes, 2017
Aim: Biotin in human serum is a potential interfering factor for streptavidin-biotin-based assays. We aimed to evaluate the effective half-life of biotin and biotin metabolites, and establish a pharmacokinetic (PK) model to simulate the time taken for ...
P. Grimsey   +6 more
semanticscholar   +1 more source

Mesoporous Silica Nanoparticles-based Smart Nanocarriers for Targeted Drug Delivery in Colorectal Cancer Therapy [PDF]

open access: yesarXiv
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, highlighting the urgent need for advanced therapeutic strategies. Nanoparticle-based drug delivery systems have emerged as a promising approach to improve the specificity and efficacy of anticancer treatments. This review examines three cutting-edge mesoporous silica
arxiv  

Electrothermal active control of preconcentrated biomolecule plugs [PDF]

open access: yesarXiv, 2019
Concentration polarization (CP) based biomolecule preconcentration is highly effective in enhancing the detection sensitivity, yet fails to precisely and dynamically control the location of the preconcentrated biomolecule plug to ensure overlap with the sensing region (e.g. immobilized molecular probes).
arxiv  

Selection of DNA nanoparticles with preferential binding to aggregated protein target. [PDF]

open access: yes, 2016
High affinity and specificity are considered essential for affinity reagents and molecularly-targeted therapeutics, such as monoclonal antibodies.
De Maere, Elisabeth   +10 more
core   +1 more source

How to Manufacture Photonic Metamaterials

open access: yesAdvanced Materials Technologies, EarlyView.
Metamaterials boast applications such as invisibility and “hyperlenses” with resolution beyond the diffraction limit, but these applications haven’t been exploited in earnest and the market for them hasn’t grown much likely because facile and economical methods for fabricating them without defect has not emerged.
Apurba Paul, Gregory Timp
wiley   +1 more source

Biotin deficiency enhances the inflammatory response of human dendritic cells.

open access: yesAmerican Journal of Physiology - Cell Physiology, 2016
The water-soluble biotin (vitamin B7) is indispensable for normal human health. The vitamin acts as a cofactor for five carboxylases that are critical for fatty acid, glucose, and amino acid metabolism.
S. Agrawal, A. Agrawal, H. Said
semanticscholar   +1 more source

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