Results 201 to 210 of about 277,237 (293)

Studies on Production of Biotin by Microorganisms

, 1966
Toshimichi Tsuboi, Chihiro Sekijo, Osamu Shoji   +2 more
openalex   +2 more sources

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Plant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH. [PDF]

Sci Adv
Zhou TT, Zheng Y, Zhang MW, Gong LH, Guo K, He XP, Liu YC, Gershenzon J, Liu Y, Li SH.   +9 more
europepmc   +1 more source

Direct Evidence for the Conversion of Dethiobiotin to Biotin in Aspergillus niger

, 1966
Judith P. Tepper, Donald B. McCormick, Lemuel D. Wright   +2 more
openalex   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

Advanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang, Shan Huang, Yan He, Weiwei Wang, Chao Tong, Mengru Ma, Manyu Zhao, Lian Yi, Klaus‐Peter Knobeloch, Peijing Zhang   +9 more
wiley   +1 more source

Effect of biotin on growth performance, serum biochemical profiles, and histomorphological changes in acetate gossypol-treated mice. [PDF]

Front Vet Sci
Luo Q, Xu T, Ainiwaer Z, Fan W, Wang C.
europepmc   +1 more source

EFFECT OF PENICILLIN ON THE PRODUCTION OF GLUTAMIC ACID BY NON-BIOTIN-REQUIRING BACTERIA

, 1964
SHIN-ICHIRÔ ÔTSUKA, Ryosuke Ishii, Isamu Shiio, Noboru Katsuya   +3 more
openalex   +2 more sources

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

Intravesical Tumor-Selective Mucoadhesive Hydrogel for Effective Chemotherapy In Murine Model. [PDF]

Int J Nanomedicine
Zheng B, Chen Z, Sun L, Quan J, Wei J, Huang B, Zhang D, Zhang P, Zhuo Y.   +8 more
europepmc   +1 more source

Amino Acid Incorporation and Biotin Deficiency

, 1963
K. Dakshinamurti, S.P. Mistry
openalex   +1 more source