Results 201 to 210 of about 467,470 (351)

Near equilibrium unbinding of streptavidin/biotin using single molecule acoustic force spectroscopy [PDF]

open access: green
Yogesh Saravanan   +6 more
openalex   +1 more source

An unusually mild case of biotin-thiamine-responsive basal ganglia disease

open access: gold, 2023
Gurnoor Lail   +2 more
openalex   +1 more source

Clinofibrate Disrupts the SNORA80B/YTHDC1‐Driven M6A Modification to Suppress Cholesterol Metabolism and Cisplatin Resistance in ESCC

open access: yesAdvanced Science, EarlyView.
This study uncovers a non‐canonical role of SNORA80B in ESCC, showing it mediates AR‐driven metabolic reprogramming via N⁶‐methyladenosine (m6A) methylation. By binding YTHDC1, SNORA80B stabilizes cholesterol‐metabolic enzyme mRNAs and promotes tumor progression. The FDA‐approved drug clinofibrate inhibits SNORA80B by disrupting cholesterol homeostasis,
Hongyu Yuan   +7 more
wiley   +1 more source

Imaging and spectroscopic comparison of multi-step methods to form DNA arrays based on the biotin–streptavidin system

open access: green, 2014
Katarzyna Gajos   +8 more
openalex   +2 more sources

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu   +14 more
wiley   +1 more source

Benefits and risks of hair, skin, and nail supplements in older adults. [PDF]

open access: yesInt J Womens Dermatol
Shing V, Aragon Sierra A, Shah AA.
europepmc   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway. [PDF]

open access: yesJ Cell Biol
Lerche M   +17 more
europepmc   +1 more source

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