Results 31 to 40 of about 381,611 (334)
Considerations in evaluating the thyroid gland in a primary care setting
Journal of Family Medicine and Primary Care, 2020 The evaluation of the thyroid can be a very involved process. A misinterpretation of the results of a thyroid function test can lead to serious complexities in a patient's management and outcome.
Jose Humphreys
doaj +1 more source
An improved smaller biotin ligase for BioID proximity labeling
Molecular Biology of the Cell, 2016 A smaller promiscuous biotin ligase for proximity biotinylation called BioID2 enables more-selective targeting of fusion proteins, requires less biotin supplementation, exhibits enhanced labeling of proximate proteins, and demonstrates the use of a ...
D. I. Kim +6 more
semanticscholar +1 more source
Self-Assembly System Based on Cyclodextrin for Targeted Delivery of Cannabidiol
Frontiers in Chemistry, 2021 Cannabidiol (CBD) is one specific kind of the cannabinoid in Cannabis sativa L with a wide range of pharmacological activities. However, the poor water solubility and specificity of CBD limits its application in pharmaceutical field.
Panyong Zhu +12 more
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Use of the "Ru-<sup>1</sup>O<sub>2</sub>-Hydrazide" System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells. [PDF]
Adv Sci (Weinh)ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Sun A +6 more
europepmc +2 more sources
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Pathological tau accumulation is implicated in a variety of neurodegenerative diseases, including frontotemporal dementia and Alzheimer’s disease.
K. M. Lohr +3 more
semanticscholar +1 more source
, 2023 The incomplete detection of glioblastoma or the remnants of surgery constitute the primary reasons underlying glioblastoma recurrence. However, the current commercial MR Gd-based contrast agents (GBCAs) are not specialized, thus posing a potentially high
Rong Zhang (44942) +15 more
core +1 more source
Production of mutant streptavidin protein and investigation of its effect on the performance of streptavidin [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Streptavidin is a versatile protein in cell science. The tetramer structure of streptavidin plays a key role in this binding, but this form interferes with some assays.
Elham Didevara +3 more
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Determination of Nine Kinds of Vitamin B Components in Healthy Food Vitamin B Tablets by HPLC
Shipin gongye ke-ji, 2022 Objective: To establish a method for the determination of nine vitamin B components in vitamin B tablets by high performance liquid chromatography-diode array detector (HPLC-DAD). Method: Folic acid was ultrasonically extracted with 0.3% ammonia solution,
Wanqing TAN, Shuling WANG, Riqing GUAN
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Biotin receptor-mediated intracellular delivery of synthetic polypeptide-protein complexes [PDF]
, 2023 Pulmonary delivery offers a non-invasive route for the administration of biotherapeutics. In this context, understanding and control of a transport into, and across cellular barriers is central to the design of delivery systems. Here, we report our study
G. Keegan +11 more
core +1 more source
BMC Biotechnology, 2010 Background Biotin is an essential enzyme cofactor that acts as a CO2 carrier in carboxylation and decarboxylation reactions. The E. coli genome encodes a biosynthetic pathway that produces biotin from pimeloyl-CoA in four enzymatic steps. The final step,
Prigge Sean T +2 more
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