Results 11 to 20 of about 292,569 (263)

Mechanisms of biotin-regulated gene expression in microbes

Synthetic and Systems Biotechnology, 2016
Biotin is an essential micronutrient that acts as a co-factor for biotin-dependent metabolic enzymes. In bacteria, the supply of biotin can be achieved by de novo synthesis or import from exogenous sources.
J. Satiaputra, K.E. Shearwin, G.W. Booker, S.W. Polyak   +3 more
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Biotin interference with laboratory test results [PDF]

Hospital Pharmacology
Introduction: Biotin interference in laboratory tests is a growing concern, particularly due to the widespread use of biotin not only as a therapeutic agent but also as a supplement in the cosmetic industry.
Strilić David Z., Stanimirov Bojan G., Đanić Maja P.   +2 more
doaj   +1 more source

Considerations in evaluating the thyroid gland in a primary care setting

Journal of Family Medicine and Primary Care, 2020
The evaluation of the thyroid can be a very involved process. A misinterpretation of the results of a thyroid function test can lead to serious complexities in a patient's management and outcome.
Jose Humphreys
doaj   +1 more source

Biotin Auxotrophy and Biotin Enhanced Germ Tube Formation in Candida albicans

Microorganisms, 2016
Due to the increased number of immunocompromised patients, infections with the pathogen Candida albicans have significantly increased in recent years. C. albicans transition from yeast to germ tubes is one of the essential factors for virulence.
Nur Ahmad Hussin, Ruvini U. Pathirana, Sahar Hasim, Swetha Tati, Jessica A. Scheib-Owens, Kenneth W. Nickerson   +5 more
doaj   +1 more source

Self-Assembly System Based on Cyclodextrin for Targeted Delivery of Cannabidiol

Frontiers in Chemistry, 2021
Cannabidiol (CBD) is one specific kind of the cannabinoid in Cannabis sativa L with a wide range of pharmacological activities. However, the poor water solubility and specificity of CBD limits its application in pharmaceutical field.
Panyong Zhu, Pin Lv, Pin Lv, Yazhou Zhang, Rongqiang Liao, Jing Liu, Rong Guo, Xuan Chen, Xiali Liao, Chuanzhu Gao, Kun Zhang, Ming Yang, Bo Yang   +12 more
doaj   +1 more source

Production of mutant streptavidin protein and investigation of its effect on the performance of streptavidin [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Streptavidin is a versatile protein in cell science. The tetramer structure of streptavidin plays a key role in this binding, but this form interferes with some assays.
Elham Didevara, Shabnam Sadoogh Abbassian, Abdolrahime Sadeghi, Hamid Abtahi   +3 more
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Determination of Nine Kinds of Vitamin B Components in Healthy Food Vitamin B Tablets by HPLC

Shipin gongye ke-ji, 2022
Objective: To establish a method for the determination of nine vitamin B components in vitamin B tablets by high performance liquid chromatography-diode array detector (HPLC-DAD). Method: Folic acid was ultrasonically extracted with 0.3% ammonia solution,
Wanqing TAN, Shuling WANG, Riqing GUAN
doaj   +1 more source

Overexpression of biotin synthase and biotin ligase is required for efficient generation of sulfur-35 labeled biotin in E. coli

BMC Biotechnology, 2010
Background Biotin is an essential enzyme cofactor that acts as a CO2 carrier in carboxylation and decarboxylation reactions. The E. coli genome encodes a biosynthetic pathway that produces biotin from pimeloyl-CoA in four enzymatic steps. The final step,
Prigge Sean T, Spalding Maroya D, Delli-Bovi Teegan A   +2 more
doaj   +1 more source

Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase

Antibiotics, 2020
Biotin protein ligase (BPL) inhibitors are a novel class of antibacterial that target clinically important methicillin-resistant Staphylococcus aureus (S. aureus). In S. aureus, BPL is a bifunctional protein responsible for enzymatic biotinylation of two
Andrew J. Hayes, Jiulia Satiaputra, Louise M. Sternicki, Ashleigh S. Paparella, Zikai Feng, Kwang J. Lee, Beatriz Blanco-Rodriguez, William Tieu, Bart A. Eijkelkamp, Keith E. Shearwin, Tara L. Pukala, Andrew D. Abell, Grant W. Booker, Steven W. Polyak   +13 more
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Construction of Orthogonal Modular Proteinaceous Nanovaccine Delivery Vectors Based on mSA-Biotin Binding

Nanomaterials, 2022
Proteinaceous nanovaccine delivery systems have significantly promoted the development of various high-efficiency vaccines. However, the widely used method of coupling the expression of scaffolds and antigens may result in their structural interference ...
Yixin Shi, Chao Pan, Kangfeng Wang, Yan Liu, Yange Sun, Yan Guo, Peng Sun, Jun Wu, Ying Lu, Li Zhu, Hengliang Wang   +10 more
doaj   +1 more source