Results 21 to 30 of about 292,569 (263)

A Stable Biotin-Streptavidin Surface Enables Multiplex, Label-Free Protein Detection by Aptamer and Aptamer-Protein Arrays Using Arrayed Imaging Reflectometry

Sensors, 2020
While label-free multiplex sensor technology enables “mixing and matching” of different capture molecules in principle, in practice this has been rarely (if ever) demonstrated. To fill this gap, we developed protocols for the preparation of mixed aptamer-
Alanna M. Klose, Benjamin L. Miller
doaj   +1 more source

Media Supplementation with Mannitol and Biotin Enhances Squalene Production of Thraustochytrium ATCC 26185 through Increased Glucose Uptake and Antioxidative Mechanisms

Molecules, 2022
Media supplementation with exogenous chemicals is known to stimulate the accumulation of important lipids produced by microalgae and thraustochytrids.
M. Kashif Ali, Biswarup Sen, Yaodong He, Mohan Bai, Guangyi Wang   +4 more
doaj   +1 more source

Scientific Opinion on Dietary Reference Values for biotin [PDF]

EFSA Journal, 2014
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for biotin.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates

Molecules, 2023
Despite the strong anticancer activity of SN38 (7-ethyl-10-hydroxy-camptothecin), the severe side effects and loss of anticancer activity caused by the lack of selectivity to cancer cells and hydrolysis of ring E prevent its clinical application.
Yi Dai, Yang Zhang, Tianxiang Ye, Yue Chen   +3 more
doaj   +1 more source

Biotin dependency due to a defect in biotin transport [PDF]

Journal of Clinical Investigation, 2002
We describe a 3-year-old boy with biotin dependency not caused by biotinidase, holocarboxylase synthetase, or nutritional biotin deficiency. We sought to define the mechanism of his biotin dependency. The child became acutely encephalopathic at age 18 months. Urinary organic acids indicated deficiency of several biotin-dependent carboxylases.
Rebecca, Mardach, Janos, Zempleni, Barry, Wolf, Martin J, Cannon, Michael L, Jennings, Sally, Cress, Jane, Boylan, Susan, Roth, Stephen, Cederbaum, Donald M, Mock   +9 more
openaire   +2 more sources

Biotin-mediated drug delivery: does the biotin transporter mediate uptake of biotin conjugates?

Journal of Enzyme Inhibition and Medicinal Chemistry
Sodium-dependent multivitamin transporter (SMVT) is a biotin transporter over-expressed in various types of cancer cells and is commonly studied for targeted drug delivery using biotin conjugates.
Ravi Tripathi, Xiaoxiao Yang, Dongning Liu, Wen Lu, Binghe Wang   +4 more
doaj   +1 more source

Transungual Delivery, Anti-Inflammatory Activity, and In Vivo Assessment of a Cyclodextrin Polypseudorotaxanes Nail Lacquer

Pharmaceutics, 2020
A new cyclodextrin polypseudorotaxanes nail lacquer (Regenail®) containing biotin, methyl sulphonyl methane (MSM), and dimethylsilanediol salicylate was developed and evaluated in vitro and in vivo.
Francisco Fernández-Campos, Francesc Navarro, Adrian Corrales, Jordi Picas, Eloy Pena, Jordi González, Francisco J. Otero-Espinar   +6 more
doaj   +1 more source

Antioxidant responses of black glutinous rice to drought and salinity stresses at different growth stages

Open Agriculture
Black glutinous rice is a local pigmented rice that attracts the interest of many people due to its high nutritional value. While cultivating, black glutinous rice may experience abiotic stresses, such as drought and salinity threat. Drought and salinity
Rudiyanto Yosefine Fetik, Alfiana Okta Hadina, Putri Anandita Linggar, Rizkiantoro Ridho, Siswoyo Tri Agus   +4 more
doaj   +1 more source

Silver Azide Nanoparticles Embedded into Silica as Energetic Nano-materials

Medžiagotyra, 2015
Silver azide is a primary high explosive that can be initiated by different means. In this work, silver azide nanoparticles were obtained, embedded into silica, and further derivatized with biotin.
Petre Ionita, Corneliu Ghica, Raluca Damian, Daniela Culita, Ioana Turcu   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source