Results 121 to 130 of about 33,953 (257)
Advanced Science, Volume 12, Issue 26, July 10, 2025.The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang +13 more
wiley +1 more source
Mechanisms Governing Precise Protein Biotinylation
Trends in Biochemical Sciences, 2017 Protein biotinylation is a key post-translational modification found throughout the living world. The covalent attachment of a biotin cofactor onto specific metabolic enzymes is essential for their activity. This modification is distinctive, in that it is carried out by a single enzyme: biotin protein ligase (BPL), an enzyme that is able to biotinylate
Louise M. Sternicki +4 more
openaire +5 more sources
Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.ABSTRACT Circulating tumor cells (CTCs) can provide non‐invasive insight into how a cancer patient responds to therapy. Their role in disease monitoring of advanced melanoma patients treated with immune checkpoint inhibitors (ICI) is unknown. CTC protein expression of human leukocyte antigen class‐I (HLA I) and programmed death ligand‐1 (PD‐L1) may ...
Matthew C. Mannino +12 more
wiley +1 more source
Off-the-shelf proximity biotinylation using ProtA-TurboID
Nature Protocols, 2022 Irene Santos-Barriopedro +2 more
semanticscholar +1 more source
A Versatile Lentiviral Delivery Toolkit for Proximity-dependent Biotinylation in Diverse Cell Types*
Molecular & Cellular Proteomics, 2018 The proximity-dependent biotinylation approach BioID is increasingly used to define proximity interactomes and subcellular organization, but is most often limited to a few easily transfectable cell lines.
Payman Samavarchi-Tehrani +3 more
semanticscholar +1 more source
Site-specific labeling of neurotrophins and their receptors via short and versatile peptide tags.
PLoS ONE, 2014 We present a toolbox for the study of molecular interactions occurring between NGF and its receptors. By means of a suitable insertional mutagenesis method we show the insertion of an 8 amino acid tag (A4) into the sequence of NGF and of 12 amino acid ...
Laura Marchetti +8 more
doaj +1 more source
Fluoride-cleavable biotinylation phosphoramidite for 5'-end-labeling and affinity purification of synthetic oligonucleotides [PDF]
, 2003 Shiyue Fang
openalex +1 more source
Genes & Development, 2018 Here, Moquin et al. show that fusion of the promiscuous biotin ligase BirAR118G with RAD18 leads to localized protein biotinylation at DNA damage sites and identify ZPET/ZNF280C as a potential DNA damage response protein. Their findings show that ZPET is
D. Moquin +13 more
semanticscholar +1 more source
Dietary Carbamazepine Administration Decreases Liver Pyruvate Carboxylase Activity and Biotinylation by Decreasing Protein and mRNA Expression in Rats [PDF]
, 2003 Sara C. Rathman +5 more
openalex +1 more source
Promiscuous protein biotinylation by Escherichia coli biotin protein ligase [PDF]
, 2004 Eunjoo Choi‐Rhee +2 more
openalex +1 more source