Results 161 to 170 of about 54,144 (311)
Mapping protein–protein interactions by mass spectrometry
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor
Protein Science, Volume 35, Issue 1, January 2026.Abstract CD1d, a non‐classical immunoreceptor, plays a central role in lipid antigen presentation to a variety of T cell types. Despite the widespread use of detergents to measure and manipulate lipid/CD1d interactions in vitro, in situ, and in vivo, the molecular basis by which detergents influence the stability of CD1d and its lipid binding ...
Uri Z. Miles +2 more
wiley +1 more source
Glycolytic enzymes - novel carbohydrate binding proteins for glycoprotein analysis [PDF]
, 2011 •The cloning, expression, purification and characterisation of recombinant prokaryotic glycolytic enzymes •The mutagenesis of prokaryotic glycolytic enzymes to generate novel recombinant carbohydrate binding proteins •The characterisation of the ...
Clarke, Paul A. +3 more
core
Promiscuous protein biotinylation by Escherichia coli biotin protein ligase [PDF]
, 2004 Eunjoo Choi‐Rhee +2 more
openalex +1 more source
Detection of protein-protein interactions using nonimmune IgG and BirA-mediated biotinylation
, 2020 Cai Huang, Ken Jacobson
openalex +1 more source
Chemistry – A European Journal, Volume 31, Issue 70, December 12, 2025.This study presents a first‐in‐class demonstration of polymeric cationic gene delivery vectors that exhibit intrinsic artificial ribonuclease activity. Based on low‐generation PAMAM dendrimers and low molecular weight PEI polymers functionalized with a fluorinated linker containing a guanidino group, our conjugates simultaneously enable gene ...
Carola Romani +4 more
wiley +1 more source
SNAC-tag for sequence-specific chemical protein cleavage. [PDF]
, 2019 Site-specific protein cleavage is essential for many protein-production protocols and typically requires proteases. We report the development of a chemical protein-cleavage method that is achieved through the use of a sequence-specific nickel-assisted ...
Dang, Bobo +5 more
core
Engineering the Link: From Genome Interaction Maps to Functional Insight
Advanced Biology, Volume 9, Issue 12, December 2025.Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen +5 more
wiley +1 more source
Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications
Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin +6 more
wiley +1 more source
Evaluation of Cell‐Extracellular Vesicle Interaction Using a Microfluidic Microsystem (CellExoChip)
Advanced Materials Technologies, Volume 10, Issue 23, December 3, 2025.A new microfluidic platform, the CellExoChip, reveals how cancer cells interact with exosomes to influence metastasis. This device isolates cancer cells and tracks their uptake exosomes and secretion of their exosomes in response to other exosomes. Lung cancer cells are showed preferentially absorb and respond to their own exosomes—hinting at a hidden ...
Nna‐Emeka Onukwugha +10 more
wiley +1 more source