Results 171 to 180 of about 54,144 (311)

Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. [PDF]

, 1990
We studied the cell-surface delivery pathways of newly synthesized membrane glycoproteins in MDCK cells and for this purpose we characterized an endogenous apical integral membrane glycoprotein.
Le Bivic, A, Mostov, K, Rodriguez-Boulan, E, Sambuy, Y   +3 more
core  

Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster

Advanced Science, Volume 12, Issue 47, December 18, 2025.
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang, Ziling Yang, Yulu Pang, Xinyue Wu, Xinrong Zhang, Tao Zhu, Xiaoyue Ding, Wei Liu, Yuan Zhou, Pengcheng Zhang, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science, Volume 12, Issue 45, December 4, 2025.
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo, Huang Yang, Xiaoming Jiang, Zheng Wang, Xuxiao He, Ying Meng, Shan Li, Min Li, Daqian Xu, Zhengwei Mao, Zhimin Lu   +10 more
wiley   +1 more source

Surface biotinylation of primary neurons to monitor changes in AMPA receptor surface expression in response to kainate receptor stimulation

, 2021
Jithin D. Nair, Jeremy M. Henley, Kevin A. Wilkinson   +2 more
openalex   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, Volume 12, Issue 45, December 4, 2025.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

Identification of potential nucleomodulins of Mycoplasma bovis by direct biotinylation and proximity-based biotinylation approaches

Frontiers in Microbiology
Mycoplasma bovis (M. bovis) is a significant bovine pathogen associated with various diseases, including bovine bronchopneumonia and mastitis resulting in substantial economic losses within the livestock industry.
Doukun Lu, Doukun Lu, Doukun Lu, Doukun Lu, Doukun Lu, Jiongxi Chen, Jiongxi Chen, Jiongxi Chen, Jiongxi Chen, Jiongxi Chen, Menghan Zhang, Menghan Zhang, Menghan Zhang, Menghan Zhang, Menghan Zhang, Yingjie Fu, Yingjie Fu, Yingjie Fu, Yingjie Fu, Yingjie Fu, Abdul Raheem, Abdul Raheem, Abdul Raheem, Abdul Raheem, Abdul Raheem, Yingyu Chen, Yingyu Chen, Yingyu Chen, Yingyu Chen, Yingyu Chen, Xi Chen, Xi Chen, Xi Chen, Xi Chen, Xi Chen, Changmin Hu, Changmin Hu, Changmin Hu, Changmin Hu, Changmin Hu, Jianguo Chen, Jianguo Chen, Jianguo Chen, Jianguo Chen, Jianguo Chen, Elise Schieck, Gang Zhao, Aizhen Guo, Aizhen Guo, Aizhen Guo, Aizhen Guo, Aizhen Guo   +51 more
doaj   +1 more source

Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution

, 2020
Brian J. Grindel, Brian J. Engel, Carolyn G. Hall, Lindsay E. Kelderhouse, Anthony Lucci, Niki M. Zacharias, Terry T. Takahashi, Steven W. Millward   +7 more
openalex   +1 more source

Stimulation of High‐Conductivity Points in Human Skin Reduces Biotin Levels to Modulate Intracellular Metabolism and Local Energy Production

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Acupuncture is a widely used therapeutic practice that targets specific points on or beneath the skin, known as acupoints. While acupoints are thought to exhibit low electrical resistance, their underlying biophysical and molecular characteristics remain incompletely understood.
Kazuki Takagaki, Kristina Todorova, Kentaro Kajiya, Andrea Clocchiatti, Stefano Sol, Fabiana Boncimino, Anna Mandinova   +6 more
wiley   +1 more source

Hyaluronan treatment of biotinylated packaging cells increases titre of progeny retrovirus affinity-captured onto paramagnetic particles [PDF]

, 2015
BACKGROUND: The polysaccharide hyaluronan is a major component of the extracellular matrix and has been observed to impact retrovirus infectivity in biological settings.
Nesbeth, DN
core  

Kinase‐Catalyzed Biotinylation of Peptides, Proteins, and Lysates

, 2012
Chamara Senevirathne, Keith Green, Mary Kay H. Pflum   +2 more
openalex   +1 more source