Results 21 to 30 of about 54,144 (311)

Streptavidin Coverage on Biotinylated Surfaces [PDF]

ACS Applied Materials & Interfaces, 2021
Biosensors and other biological platform technologies require the functionalization of their surface with receptors to enhance affinity and selectivity. Control over the functionalization density is required to tune the platform's properties. Streptavidin (SAv) monolayers are widely used to immobilize biotinylated proteins, receptors, and DNA.
P. H. Erik Hamming, Jurriaan Huskens
openaire   +3 more sources

Coupling of Cell Surface Biotinylation and SILAC-Based Quantitative Proteomics Identified Myoferlin as a Potential Therapeutic Target for Nasopharyngeal Carcinoma Metastasis

Frontiers in Cell and Developmental Biology, 2021
Distant metastasis is a major cause of treatment failure in nasopharyngeal carcinoma (NPC) patients. Cell surface proteins represent attractive targets for cancer diagnosis or therapy. However, the cell surface proteins associated with NPC metastasis are
Maoyu Li, Maoyu Li, Fang Peng, Guoqiang Wang, Xujun Liang, Meiying Shao, Zhuchu Chen, Zhuchu Chen, Yongheng Chen, Yongheng Chen, Yongheng Chen   +10 more
doaj   +1 more source

Optical Sensors and Actuators for Probing Proximity-Dependent Biotinylation in Living Cells

Frontiers in Cellular Neuroscience, 2022
Proximity-dependent biotinylation techniques have been gaining wide applications in the systematic analysis of protein-protein interactions (PPIs) on a proteome-wide scale in living cells.
Rui Chen, Ningxia Zhang, Yubin Zhou, Ji Jing   +3 more
doaj   +1 more source

An unexpected strategy to alleviate hypoxia limitation of photodynamic therapy by biotinylation of photosensitizers

Nature Communications, 2022
The most common working mechanism of photodynamic therapy is based on high-toxicity singlet oxygen, which is called Type II photodynamic therapy. But it is highly dependent on oxygen consumption.
Jing An, Shanliang Tang, Gaobo Hong, Wenlong Chen, Miaomiao Chen, Jitao Song, Zhiliang Li, Xiaojun Peng, Fengling Song, Wenhong Zheng   +9 more
semanticscholar   +1 more source

A Straightforward Interpretation of Proximity Labeling through Direct Biotinylation Analysis. [PDF]

ACS Omega
Kim HB, Kim KE.
europepmc   +2 more sources

Juvenile Hormone Membrane Signaling Enhances its Intracellular Signaling Through Phosphorylation of Met and Hsp83

Frontiers in Physiology, 2022
Juvenile hormone (JH) regulates insect development and reproduction through both intracellular and membrane signaling, and the two pathways might crosstalk with each other.
Yue Gao, Nan Chen, Xiangle Zhang, Emma Y. Li, Wei Luo, Jie Zhang, Wenqiang Zhang, Sheng Li, Sheng Li, Jian Wang, Suning Liu, Suning Liu   +11 more
doaj   +1 more source

Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells

Communications Biology, 2022
Proximity-dependent biotinylation (PDB) combined with mass spectrometry analysis has established itself as a key technology to study protein-protein interactions in living cells. A widespread approach, BioID, uses an abortive variant of the E.
Lea Kubitz, Sebastian Bitsch, Xiyan Zhao, Kerstin Schmitt, Lukas Deweid, Amelie Roehrig, Elisa Cappio Barazzone, O. Valerius, H. Kolmar, J. Béthune   +9 more
semanticscholar   +1 more source

PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II

Cell Reports, 2022
Summary: Intrahepatic cholangiocarcinoma (ICC) contains abundant myofibroblasts derived from hepatic stellate cells (HSCs) through an activation process mediated by TGF-β.
Liankang Sun, Yuanguo Wang, Xianghu Wang, Amaia Navarro-Corcuera, Sumera Ilyas, Nidhi Jalan-Sakrikar, Can Gan, Xinyi Tu, Yu Shi, Kangsheng Tu, Qingguang Liu, Zhenkun Lou, Haidong Dong, Arlene H. Sharpe, Vijay H. Shah, Ningling Kang   +15 more
doaj   +1 more source

Biotin protein ligase as you like it: Either extraordinarily specific or promiscuous protein biotinylation

Proteins: Structure, Function, and Bioinformatics, 2023
Biotin (vitamin H or B7) is a coenzyme essential for all forms of life. Biotin has biological activity only when covalently attached to a few key metabolic enzyme proteins.
J. Cronan
semanticscholar   +1 more source

A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues

Nature Communications, 2022
Proteolysis-targeting chimaeras (PROTACs) as well as molecular glues such as immunomodulatory drugs (IMiDs) and indisulam are drugs that induce interactions between substrate proteins and an E3 ubiquitin ligases for targeted protein degradation. Here, we
S. Yamanaka, Yuto Horiuchi, Saya Matsuoka, Kohki Kido, K. Nishino, Mayaka Maeno, N. Shibata, H. Kosako, T. Sawasaki   +8 more
semanticscholar   +1 more source