Streptavidin-Saporin: Converting Biotinylated Materials into Targeted Toxins
Toxins, 2023 Streptavidin-Saporin can be considered a type of ‘secondary’ targeted toxin. The scientific community has taken advantage of this conjugate in clever and fruitful ways using many kinds of biotinylated targeting agents to send saporin into a cell selected
Leonardo R. Ancheta +4 more
doaj +1 more source
Novel components of the Toxoplasma inner membrane complex revealed by BioID. [PDF]
, 2015 UNLABELLED:The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a supporting cytoskeletal network. The IMC plays important roles in
Bell, Hannah N +11 more
core +3 more sources
Dynamin- and Rab5-Dependent Endocytosis of a Ca2+-Activated K+ Channel, KCa2.3 [PDF]
, 2012 Regulation of the number of ion channels at the plasma membrane is a critical component of the physiological response. We recently demonstrated that the Ca2+-activated K+ channel, KCa2.3 is rapidly endocytosed and enters a Rab35- and EPI64C-dependent ...
Agustin Guerrero-Hernandez +5 more
core +10 more sources
ABCC6 is a basolateral plasma membrane protein [PDF]
, 2013 RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A. +11 more
core +4 more sources
Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts
Journal of Lipid Research, 2006 Previous studies have suggested that HDL retroendocytosis may play a role in scavenger receptor class B type I (SR-BI)-dependent selective lipid uptake in a cell-specific manner.
Bing Sun +4 more
doaj +1 more source
Application of Skyline for Analysis of Protein–Protein Interactions In Vivo
Molecules, 2021 Quantitative and qualitative analyses of cell protein composition using liquid chromatography/tandem mass spectrometry are now standard techniques in biological and clinical research.
Arman Kulyyassov
doaj +1 more source
M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes [PDF]
, 2017 Morphine inefficiency to induce the internalization of mu opioid (MOP) receptors observed in numerous experimental models constitutes a paradigm of G-protein coupled receptor (GPCR) functional selectivity.
Alvarez-Curto, Elisa +2 more
core +1 more source
Comparison between a direct-flow SPR immunosensor for ampicillin and a competitive conventional amperometric device: analytical features and possible applications to real samples [PDF]
, 2017 In this research, we developed a direct-flow surface plasmon resonance (SPR) immunosensor for ampicillin to perform direct, simple, and fast measurements of this important antibiotic.
Campanella, Luigi +6 more
core +2 more sources
Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis [PDF]
, 2020 The homing of Endothelial Progenitor Cells (EPCs) to tumor angiogenic sites has been described as a multistep process, involving adhesion, migration, incorporation and sprouting, for which the underlying molecular and cellular mechanisms are yet to be ...
Bieback, Karen +6 more
core +1 more source
Cell-Type-Specific Proteomics: A Neuroscience Perspective
Proteomes, 2018 Cell-type-specific analysis has become a major focus for many investigators in the field of neuroscience, particularly because of the large number of different cell populations found in brain tissue that play roles in a variety of developmental and ...
Rashaun S. Wilson, Angus C. Nairn
doaj +1 more source