Results 61 to 70 of about 49,644 (261)

Chlamydia suis, an emerging Chlamydiaceae species in pigs? [PDF]

open access: yes, 2010
Chlamydiaceae are Gram-negative obligate intracellular bacteria that can infect a broad range of animals and humans. Chlamydial infection of livestock, companion animals, and other animals may result in conjunctivitis, enteritis, pneumonia, abortion ...
Beeckman, Delphine Sylvie Anne   +7 more
core   +1 more source

Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures [PDF]

open access: yes, 2019
The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites.
Andrews, Peter M.   +11 more
core   +2 more sources

Precisely biotinylated RNA [PDF]

open access: yesNature Methods, 2005
Using unnatural base pairs, researchers have site-specifically biotinylated RNA, allowing them to immobilize an aptamer on a chip and detect its interaction with a target protein.
openaire   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

open access: yesAdvanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier   +10 more
wiley   +1 more source

Biotinylation as a tool to enhance the uptake of small molecules in Gram-negative bacteria.

open access: yesPLoS ONE, 2021
Antibiotic resistance is a major public health concern. The shrinking selection of effective antibiotics and lack of new development is making the situation worse.
Ankit Pandeya   +6 more
doaj   +2 more sources

Biotinylated Cyclooligosaccharides for Paclitaxel Solubilization [PDF]

open access: yesMolecules, 2018
The poor water solubility of paclitaxel causes significant problems in producing cancer therapeutic formulations. Here, we aimed to solubilize paclitaxel using biocompatible cyclic carbohydrates. Generally recognized as safe, labeled β-cyclodextrin (β-CD), a cyclic α-1,4-glucan consisting of seven glucoses, was prepared, and bio-sourced ...
Cho, Eunae, Jung, Seunho
openaire   +2 more sources

Responsive Visible‐Wavelength Metasurfaces from Porous Silicon Based on Fano Guided‐Mode Resonance

open access: yesAdvanced Optical Materials, EarlyView.
The article introduces mesoporous silicon metasurfaces (pSi‐MS) supporting Fano guided‐mode resonances in the visible regime. By combining top‐down lithographic patterning of 2D gratings with bottom‐up electrochemical porosification, the approach realizes a new class of responsive metasurfaces, enabling highly sensitive and portable platforms for small
Tomoshree Dash   +4 more
wiley   +1 more source

Diversity in functional organization of class I and class II biotin protein ligase. [PDF]

open access: yesPLoS ONE, 2011
The cell envelope of Mycobacterium tuberculosis (M. tuberculosis) is composed of a variety of lipids including mycolic acids, sulpholipids, lipoarabinomannans, etc., which impart rigidity crucial for its survival and pathogenesis.
Sudha Purushothaman   +3 more
doaj   +1 more source

Direct measurement of transcription rates reveals multiple mechanisms for configuration of the Arabidopsis ambient temperature response [PDF]

open access: yes, 2014
Background Sensing and responding to ambient temperature is important for controlling growth and development of many organisms, in part by regulating mRNA levels.
Costa, Maria J. (Maria João)   +4 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

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