Results 61 to 70 of about 33,953 (257)

Application of Cadaverine to Inhibit Biotin Biosynthesis in Plants

Bio-Protocol, 2022
Biotin is an essential vitamin in plants. However, characterization of biotin deficiency has been limited by embryo lethality in mutants, which can only be rescued by supplementation of biotin.
Nicole Gibbs, Shih- Su, Patrick Masson
doaj   +1 more source

Biotinylated Primary Amines

Proceedings of The 14th International Electronic Conference on Synthetic Organic Chemistry, 2010
In the frame of a biotinylation program of biologically active amines we synthesized two amides from 2-phenetylamine and 3,4-dimethoxybenzylamine, that were fully characterized by means of multinuclear NMR spectroscopy.
Clarissa P. Frizzo, Rosa M. Claramunt, José Elguero, Dionisia Sanz   +3 more
openaire   +2 more sources

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar, David S. Lee, Daniel Cabrerizo‐Aguado, Rachel Werther, Kevin Alexander Estrada Alamo, Yan Ting Zhao, Adam Nguyen, Irina Kopyeva, Buwei Huang, Jing Li, Yuxin Hao, Xinting Li, Aritza Brizuela‐Velasco, Analisa Murray, Stacey Gerben, Anindya Roy, Cole A. DeForest, Timothy Springer, Hannele Ruohola‐Baker, Jonathan A. Cooper, Melody G. Campbell, Jose Maria Manero, Maria‐Pau Ginebra, David Baker   +25 more
wiley   +1 more source

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

bioRxiv, 2020
Biotin-labeled molecular probes, comprising specific regions of the SARS-CoV-2 spike, would be helpful in the isolation and characterization of antibodies targeting this recently emerged pathogen.
T. Zhou, I-Ting Teng, A. Olia, G. Cerutti, J. Gorman, Alexandra F. Nazzari, W. Shi, Y. Tsybovsky, Lingshu Wang, Shuishu Wang, Baoshan Zhang, Yi Zhang, Phinikoula S. Katsamba, Yuliya Petrova, Bailey B Banach, Ahmed S. Fahad, Lihong Liu, Sheila N. Lopez Acevedo, Bharat Madan, M. O. de Souza, Xiaoli Pan, Pengfei Wang, Jacy R Wolfe, M. Yin, D. Ho, Emily Phung, Anthony T. DiPiazza, Lauren A. Chang, O. Abiona, Kizzmekia S. Corbett, B. Dekosky, B. Graham, J. Mascola, J. Misasi, Tracy Ruckwardt, N. Sullivan, L. Shapiro, P. Kwong   +37 more
semanticscholar   +1 more source

Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance

Advanced Materials, EarlyView.
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee, Heung Jin Jeon, Dohyub Jang, Deukhee Lee, Solbi Kim, Minju Han, Sharon Jiyoon Jung, Jung‐Hyun Lee, Jia Choi, Dong Ha Kim, Dong June Ahn, Keri Kim, Sehoon Kim, Hyo‐Jin Lee, SeungBeum Suh   +14 more
wiley   +1 more source

In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

bioRxiv, 2019
The GTPases of the Ras superfamily regulate cell growth, membrane traffic and the cytoskeleton, and a wide range of diseases are caused by mutations in particular members. They function as switchable landmarks with the active GTP-bound form recruiting to
A. Gillingham, J. Bertram, Farida Begum, S. Munro   +3 more
semanticscholar   +1 more source

High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme

Nucleic Acids Research, 2020
Guanine-rich, single-stranded DNAs and RNAs that fold to G-quadruplexes (GQs) are able to complex tightly with heme and display strongly enhanced peroxidase activity.
Prince Kumar Lat, Kun Liu, Dev N Kumar, K. K. Wong, E. Verheyen, D. Sen   +5 more
semanticscholar   +1 more source

Diversity in functional organization of class I and class II biotin protein ligase. [PDF]

PLoS ONE, 2011
The cell envelope of Mycobacterium tuberculosis (M. tuberculosis) is composed of a variety of lipids including mycolic acids, sulpholipids, lipoarabinomannans, etc., which impart rigidity crucial for its survival and pathogenesis.
Sudha Purushothaman, Karthikeyan Annamalai, Anil K Tyagi, Avadhesha Surolia   +3 more
doaj   +1 more source

OXavidin for Tissue Targeting Biotinylated Therapeutics [PDF]

BioMed Research International, 2009
Avidin is a glycoprotein from hen egg white that binds biotin with very high affinity. Here we describe OXavidin, a product containing aldehyde groups, obtained by ligand‐assisted sugar oxidation of avidin by sodium periodate. OXavidin chemically reacts with cellular and tissue proteins through Schiff′s base formation thus residing in tissues for weeks
De Santis, Rita, Albertoni, Claudio, Rosi, Antonio, Leoni, Barbara, Petronzelli, Fiorella, D'Alessio, Valeria, Nucera, Eleonora, Salvatori, Giovanni, Paganelli, Giovanni, Verdoliva, Antonio, Carminati, Paolo, Nuzzolo, Carlo Antonio   +11 more
openaire   +3 more sources

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

Advanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali, Sanjana Srikant, Md Fahim Al Fattah, Nicole G. Barra, Darryl Chan, Dayan Ban, Jonathan D. Schertzer, Mahla Poudineh   +7 more
wiley   +1 more source