Results 71 to 80 of about 33,953 (257)
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation
Nucleic Acids Research, 2020 During interphase centromeres often coalesce into a small number of chromocenters, which can be visualized as distinct, DAPI dense nuclear domains.
N. Y. Kochanova +8 more
semanticscholar +1 more source
Analysis of Chemokine Receptor Trafficking by Site-Specific Biotinylation. [PDF]
PLoS ONE, 2016 Chemokine receptors undergo internalization and desensitization in response to ligand activation. Internalized receptors are either preferentially directed towards recycling pathways (e.g. CCR5) or sorted for proteasomal degradation (e.g. CXCR4). Here we
Marcel Liebick +2 more
doaj +1 more source
Advanced Science, EarlyView.Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei +11 more
wiley +1 more source
BiomedicinesThe availability of yeast surface display nanobody (Nb) libraries offers a convenient way to acquire antigen-specific nanobodies that may be useful for protein structure–function studies and/or therapeutic applications, complementary to the conventional ...
Yudong Sun +4 more
doaj +1 more source
Journal of Experimental Life Science, 2019 Protein has been known as an important macromolecule which has a vital role among the living organism. One of the most interesting protein is Arc1p, which is a yeast-specific tRNA-binding protein.
Restu Nugraha +2 more
doaj +1 more source
Journal of Cell Science, 2019 The use of proximity-dependent biotinylation assays coupled to mass spectrometry (PDB-MS) has changed the field of protein–protein interaction studies.
Marc Larochelle +3 more
semanticscholar +1 more source
The generality of kinase-catalyzed biotinylation [PDF]
Bioorganic & Medicinal Chemistry, 2016 Kinase-catalyzed protein phosphorylation is involved in a wide variety of cellular events. Development of methods to monitor phosphoproteins in normal and diseased states is critical to fully characterize cell signaling. Towards phosphoprotein analysis tools, our lab reported kinase-catalyzed labeling where γ-phosphate modified ATP analogs are utilized
Mary Kay H. Pflum +4 more
openaire +3 more sources
Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems
bioRxiv, 2019 The use of proximity-dependent biotin labelling (PDL) approaches coupled with mass spectrometry recently greatly advanced the identification of protein-protein interactions and study of protein complexation.
Deepanksha Arora +16 more
semanticscholar +2 more sources
Biological functions of biotinylated histones [PDF]
The Journal of Nutritional Biochemistry, 2005 Histones H1, H2A, H2B, H3 and H4 are DNA-binding proteins that mediate the folding of DNA into chromatin. Various posttranslational modifications of histones regulate processes such as transcription, replication and repair of DNA. Recently, a novel posttranslational modification has been identified: covalent binding of the vitamin biotin to lysine ...
Gabriela Camporeale +6 more
openaire +3 more sources
Journal of Biological Chemistry, 2020 Stimulator of interferon genes (STING) mediates cytosolic DNA-induced innate immune signaling via membrane trafficking. The global identification of proteins that spatiotemporally interact with STING will provide a better understanding of its trafficking
Kou Motani, H. Kosako
semanticscholar +1 more source