Results 1 to 10 of about 93,640 (146)
ACS ES&T water, 2021 Complex microbial communities in environmental systems play a key role in the detoxification of chemical contaminants by transforming them into less active metabolites or by complete mineralization. Biotransformation, i.e., transformation by microbes, is
K. Fenner +6 more
semanticscholar +1 more source
Archives of Toxicology, 2021 Given the strong trend to implement zebrafish (Danio rerio) embryos as translational model not only in ecotoxicological, but also toxicological testing strategies, there is an increasing need for a better understanding of their capacity for xenobiotic ...
Ann-Kathrin Loerracher, T. Braunbeck
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Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms.
Environmental Science and Technology, 2020 Biotransformation plays a crucial role in regulating the bioaccumulation potential and toxicity of organic compounds in organisms but is, in general, poorly understood for emerging contaminants.
Q. Fu +7 more
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Detoxification of Mycotoxins through Biotransformation
Toxins, 2020 Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well
Peng Li +6 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2020 Selenium (Se) in soil mainly consists of selenite, selenate, and elemental Se. However, little is known about the mechanism involved in the uptake and biotransformation of elemental Se by plants.
Kang-Jun Wang +7 more
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Biotransformation: Impact and Application of Metabolism in Drug Discovery.
ACS Medicinal Chemistry Letters, 2020 Biotransformation has a huge impact on the efficacy and safety of drugs. Ultimately the effects of metabolism can be the lynchpin in the discovery and development cycle of a new drug. This article discusses the impact and application of biotransformation
Julia Shanu-Wilson +5 more
semanticscholar +1 more source
Patents on Endophytic Fungi Related to Secondary Metabolites and Biotransformation Applications
Journal of Fungi, 2020 Endophytic fungi are an important group of microorganisms and one of the least studied. They enhance their host’s resistance against abiotic stress, disease, insects, pathogens and mammalian herbivores by producing secondary metabolites with a wide ...
Daniel Torres-Mendoza +2 more
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Mycotoxins: Biotransformation and Bioavailability Assessment Using Caco-2 Cell Monolayer
Toxins, 2020 The determination of mycotoxins content in food is not sufficient for the prediction of their potential in vivo cytotoxicity because it does not reflect their bioavailability and mutual interactions within complex matrices, which may significantly alter ...
Van Nguyen Tran, J. Viktorová, T. Ruml
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Recent Advances in Biotransformation of Saponins
Molecules, 2019 Saponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants.
Yi He +9 more
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Glutathione-mediated biotransformation in the liver modulates nanoparticle transport
Nature Nanotechnology, 2019 Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even ...
Xingya Jiang, Bujie Du, Jie Zheng
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