Results 201 to 210 of about 71,056 (300)

Saffron aqueous extract effects on paraquat and glyphosate concentration in common carp (Cyprinus carpio) tissues

open access: yesAgricultural &Environmental Letters, Volume 11, Issue 2, December 2026.
Reduced bioaccumulation of PQ and GLY by saffron extract in Common carp (Cyprinus carpio) tissues Abstract Herbicides such as paraquat (PQ) and glyphosate (GLY) pose ecological and public health risks because of their persistence, bioaccumulation, and toxicity to aquatic organisms. This study evaluated whether aqueous saffron extract (Crocus sativus L.)
Hossein Hammami, Javad Kharkan
wiley   +1 more source

Beyond Total Content: Assessing the Bioaccessibility of Metals in Tattoo Inks Using Validated Extraction Media

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT A validated analytical workflow is presented for determining total and bioaccessible concentrations of regulated elements in tattoo inks, addressing the lack of harmonized protocols for comparing extraction approaches in complex matrices. Although current legislation defines limits for soluble fractions of selected metals, it does not specify ...
Maria Luisa Astolfi   +3 more
wiley   +1 more source

Immune-driven biotransformation of gold nanosheets by human primary neutrophils. [PDF]

open access: yesNanoscale Adv
Poddar S   +6 more
europepmc   +1 more source

PFAS Vadose Zone Mass Discharge at an AFFF‐Impacted Site: 1. Validation Based on a Multiple Lines‐of‐Evidence Approach

open access: yesRemediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT Questions have recently been raised about the suitability of using porewater samples collected with suction lysimeters to estimate per‐ and polyfluoroalkyl substances (PFAS) mass discharge in the vadose zone. Multiple lines of evidence were evaluated to determine if porewater samples collected during a data gaps investigation in the former ...
Grant R. Carey   +8 more
wiley   +1 more source

Fragment Coverage: Unified Visualization and Quantitative Assessment of MS/MS Fragmentation Supports Metabolite Identification in Macromolecule Drug Metabolism Studies

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale Peptides and oligonucleotides are increasingly used as therapeutic agents, making the identification and structural elucidation of their metabolites a critical step in drug development. Liquid chromatography–mass spectrometry (LC‐MS/MS) is the primary analytical technique for this purpose; however, extensive backbone fragmentation ...
Paula Cifuentes   +3 more
wiley   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2629-2642, October 2026.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian   +4 more
wiley   +1 more source

Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans

open access: yesBiomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT RU 58841 is a nonsteroidal antiandrogen, developed for the treatment of androgen‐dependent conditions. This study aimed to characterize the human metabolism of RU 58841 for the first time and to assess its systemic exposure following topical administration.
Aylin Okutan   +4 more
wiley   +1 more source

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