Results 181 to 190 of about 62,756 (305)

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 43-54, July 2026.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Stereoselective 15α-hydroxylation of androsta-1,4-diene-3,17-dione by <i>Gibberella</i> sp. for efficient production of 15α-OH-ADD and 15α-OH-AD. [PDF]

RSC Adv
He R, Song M, Fu R, Jin Y, Li S, Wang F, Zhang G, Song Y, Xu W.   +8 more
europepmc   +1 more source

Flavour Ester Synthesis by Immobilized Lipases: A Research Overview With Industrial Relevance

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 721-741, July 2026.
Research landscape of flavour ester synthesis by immobilized lipases, highlighting enzymatic routes, major research themes and aspects related to industrial relevance, including enzyme reuse, solvent‐free systems, process intensification and scale‐up potential.
Nicole Marasca, Francisco Lucas Chaves Almeida, Rebeca Luana Carneiro, Marcus Bruno Soares Forte   +3 more
wiley   +1 more source

Biological Detoxification of Mycotoxins by Lactic Acid Bacteria: Safeguarding Food from Fungal Contaminants. [PDF]

Toxins (Basel)
Tabassum N, Kim M, Kim TH, Jo DM, Jung WK, Kim YM, Khan F.   +6 more
europepmc   +1 more source

Xenobiotic biotransformation in aquatic organisms

Aquatic animals are exposed to a variety of natural and anthropogenic xenobiotics. Biotransformation of xenobiotics was examined in three aquatic animals: a primitive mollusc (chiton); a shellfish which is an important human food source (oyster); and, a ...
Schlenk, Daniel K.
core  

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source

Synthesis and Cytotoxicity of Complex Betulinic Acid Amides. [PDF]

ACS Omega
Wimmerová M, Kyjaková P, Šaman D, Wimmer Z.   +3 more
europepmc   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1300-1311, July 2026.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Complete genome sequencing of <i>Lactobacillus pentosus</i> HP-B1718 and identification of the key enzyme for liquiritin biotransformation. [PDF]

Front Microbiol
Tan ZW, Mao XR, Qi QM, Wang XH, Liu MJ, Wu H, Li LF, Fan ZS, Hou SY.   +8 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source