Results 251 to 260 of about 62,756 (305)
Some of the next articles are maybe not open access.
Biotransformation of Sevoflurane
Anesthesia & Analgesia, 1995Several characteristics of sevoflurane biotransformation are apparent from the preceding investigations. Metabolism is rapid, with fluoride and HFIP appearing in plasma within minutes after the start of sevoflurane administration (38-40,51). Peak plasma fluoride concentrations generally occur within approximately 1 h after the termination of ...
openaire +2 more sources
Toxicologic Pathology, 1988
About 4 million compounds have been described by chemists, and some 60,000 are presently on the market. The search for new chemicals with better properties and less toxicity continues, and future life quality will depend on our ability to find the safest compounds in each field of application.
openaire +2 more sources
About 4 million compounds have been described by chemists, and some 60,000 are presently on the market. The search for new chemicals with better properties and less toxicity continues, and future life quality will depend on our ability to find the safest compounds in each field of application.
openaire +2 more sources
Biotransformations of Steroids
Critical Reviews in Biotechnology, 1988Different types of microbiological transformation of steroids are reviewed, with special attention given to bioconversions applied in the manufacturing of steroid hormones, i.e., 11 alpha- 11 beta-, 16 alpha-, 17 alpha-hydroxylations and 1-dehydrogenation.
Leon Sedlaczek, Leland L. Smith
openaire +2 more sources
Biotransformation of alkaloids
2001Biotransformations of alkaloids over the last decade have continued to encompass a wide variety of substrates and enzymes. The elucidation of novel alkaloid biosynthetic and catabolic pathways will continue to furnish new biocatalysts for the synthetic organic chemist.
Deborah A, Rathbone +2 more
openaire +3 more sources
The biotransformation of nitroglycerin
Biochemical Pharmacology, 1965Abstract The transformation of nitroglycerin (NG) was accomplished by the formation of 1,2- and 1,3-dinitroglycerin. The dinitrates were resistant to further degradation and appeared as the urinary metabolites after the administration of NG. The dinitroglycerins were less active coronary vasodilators and blood pressure depressants than NG.
P, Needleman, J C, Krantz
openaire +2 more sources
Biotransformations with Peroxidases
1999Enzymes are chiral catalysts and are able to produce optically active molecules from prochiral or racemic substrates by catalytic asymmetric induction. One of the major challenges in organic synthesis is the development of environmentally acceptable chemical processes for the preparation of enantiomerically pure compounds, which are of increasing ...
W, Adam +6 more
openaire +2 more sources
Hepatocytes: The powerhouse of biotransformation
The International Journal of Biochemistry & Cell Biology, 2012Liver is the most important organ involved in biotransformation of xenobiotics. Within the main organisational unit, the hepatocyte, is an assembly of enzymes commonly classified as phase I and phase II enzymes. The phase I enzymes principally cytochrome P450 catalyse both oxidative and reductive reactions of a bewildering number of xenobiotics.
Danielle K, Sevior +2 more
openaire +2 more sources
1996
Now in its seventh outstanding volume, Biotransformations has become established as a unique and important source for those involved in the discovery and development of new compounds. It broadly covers the scientific literature for the period 1987 to 1994. The series provides a complete survey of the biotransformations, in vertebrates, of the following:
D Kirkpatrick +4 more
openaire +1 more source
Now in its seventh outstanding volume, Biotransformations has become established as a unique and important source for those involved in the discovery and development of new compounds. It broadly covers the scientific literature for the period 1987 to 1994. The series provides a complete survey of the biotransformations, in vertebrates, of the following:
D Kirkpatrick +4 more
openaire +1 more source
Biotransformation of Methoxyflurane
International Anesthesiology Clinics, 1974R I, Mazze, M J, Cousins
openaire +2 more sources