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Biotransformation of 8:2 Fluorotelomer Alcohol in Soil from Aqueous Film-Forming Foams (AFFFs)-Impacted Sites under Nitrate-, Sulfate-, and Iron-Reducing Conditions.

Environmental Science and Technology, 2022
The environmental fate of per- and polyfluoroalkyl substances (PFAS) in aqueous film-forming foams (AFFFs) remains largely unknown, especially under the conditions representative of natural subsurface systems.
Pengchao Yan   +8 more
semanticscholar   +1 more source

Digoxin biotransformation

Clinical Pharmacology and Therapeutics, 1984
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault   +6 more
openaire   +2 more sources

Digoxigenin biotransformation

Clinical Pharmacology and Therapeutics, 1982
Two healthy subjects took 3H-digoxigenin-12 alpha and unlabeled digoxigenin. Metabolites were assayed by high-pressure liquid chromatography (HPLC) in serum and urine. Of the tritium activity in the serum at 30 min, less than 26% chromatographed with digoxigenin; the rest chromatographed as metabolites, most of which were polar.
H, Gault   +3 more
openaire   +2 more sources

Biotransformation of vulgarin

Planta Medica, 2012
Using a standard two-stage fermentation technique, the fungus Beauveria bassiana (ATCC 7159) was found to convert the eudesmanolide vulgarin (1) to 1α,4α-dihydroxy-5αH,6,11βH-eudesman-6,12-olide (2). The use of the yeastHansenula anomala ATCC 20170 instead, produced the less polar 4α-hydroxy-1-oxo-5αH,6,11βH-eudesman-6,12-olide(3), in addition to the ...
Khaled Y, Orabi   +3 more
openaire   +2 more sources

In Vitro and In Vivo Biotransformation Profiling of 6PPD-Quinone toward Their Detection in Human Urine.

Environmental Science and Technology
The antioxidant N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidized quinone product 6PPD-quinone (6PPD-Q) in rubber have attracted attention due to the ecological risk that they pose.
Man Deng   +3 more
semanticscholar   +1 more source

Molecular Mechanisms, Characterization Methods, and Utilities of Nanoparticle Biotransformation in Nanosafety Assessments.

Small, 2020
It is a big challenge to reveal the intrinsic cause of a nanotoxic effect due to diverse branches of signaling pathways induced by engineered nanomaterials (ENMs). Biotransformation of toxic ENMs involving biochemical reactions between nanoparticles (NPs)
Xiaoming Cai   +7 more
semanticscholar   +1 more source

Mucosal Biotransformation

Toxicologic Pathology, 1988
About 4 million compounds have been described by chemists, and some 60,000 are presently on the market. The search for new chemicals with better properties and less toxicity continues, and future life quality will depend on our ability to find the safest compounds in each field of application.
openaire   +2 more sources

In-vivo biotransformation of citrus functional components and their effects on health

Critical reviews in food science and nutrition, 2020
Citrus, one of the most popular fruits worldwide, contains various functional components, including flavonoids, dietary fibers (DFs), essential oils (EOs), synephrines, limonoids, and carotenoids.
A. Karn   +8 more
semanticscholar   +1 more source

How do biocatalysis and biotransformation affect Citrus dietary flavonoids chemistry and bioactivity? A review

Critical Reviews in Biotechnology, 2020
Flavonoids, especially flavanones, flavones and polymethoxyflavones (PMFs) are distinctive bioactive compounds of Citrus fruits. Citrus peel and juice by-products potentially represent rich sources of these Citrus flavonoids that exhibit a myriad of ...
Z. T. Shakour, Nesrin M. Fayek, M. Farag
semanticscholar   +1 more source

Bioconcentration, biotransformation, and thyroid endocrine disruption of decabromodiphenyl ethane (DBDPE), a novel brominated flame retardant, in zebrafish larvae.

Environmental Science and Technology, 2019
The brominated flame retardant decabromodiphenyl ethane (DBDPE), an alternative to decabrominated diphenyl ether (BDE209), has become a widespread environmental contaminant, but its possible toxic effects to wildlife remain unknown.
Xiaocheng Wang   +8 more
semanticscholar   +1 more source

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