Results 41 to 50 of about 161,017 (342)

Biotransformation: Impact and Application of Metabolism in Drug Discovery.

open access: yesACS Medicinal Chemistry Letters, 2020
Biotransformation has a huge impact on the efficacy and safety of drugs. Ultimately the effects of metabolism can be the lynchpin in the discovery and development cycle of a new drug. This article discusses the impact and application of biotransformation
Julia Shanu-Wilson   +5 more
semanticscholar   +1 more source

Green technology meets ecotoxicology

open access: yesCroatian Journal of Food Science and Technology, 2016
By applying concept and principles of green chemistry into different technological processes, green technologies are developed. The environmental and economic benefits of “green” approach is achieved through several directions, such as the use of ...
Kristina Radošević   +4 more
doaj   +1 more source

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]

open access: yes, 2000
We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
Boonstra, B   +4 more
core   +2 more sources

Biotransformation of ent-beyerenes with mucor plumbeus [PDF]

open access: yes, 2013
Indexación: Web of Science; Scielo.ABSTRACT The microbiological transformation of ent-beyer-15-en-18-ol 1 and ent-beyer-15-en-19-ol 2, using Mucorplumbeus, resulted in hydroxylated products.
Chamy, María Cristina   +3 more
core   +1 more source

Pollutants Biodegradation by Fungi [PDF]

open access: yes, 2009
Revisión sobre los mecanismos de detoxificación de contaminantes por hongosOne of the major problems facing the industrialized world today is the contamination of soils, ground water, sediments, surfacewater and air with hazardous and toxic chemicals ...
Aleu Casatejada, Josefina   +2 more
core   +2 more sources

The role of microorganisms on biotransformation of brewers’ spent grain

open access: yesApplied Microbiology and Biotechnology, 2020
Brewers’ spent grain (BSG) is the most abundant by-product of brewing. Due to its microbiological instability and high perishability, fresh BSG is currently disposed of as low-cost cattle feed.
A. Bianco   +5 more
semanticscholar   +1 more source

Hairy root culture of white mulberry (Morus alba L.) for a source of tyrosinase inhibitors

open access: yesJournal of Biological Research, 2020
White mulberry (Morus alba L.) root was reported to contain potential tyrosinase inhibitors such as norartocarpetin, streppogenin, oxyresveratrol (5, 7, 2′, 4′-tetrahydroxy-flavavone) and 2-arylbenzofuran.
Hanh Thi My Nguyen   +3 more
doaj   +1 more source

Microbiological and physicochemical characterization of a traditionally fermented corn product: "Champús"

open access: yesVitae, 2023
Background: Many native fermented foods in Latin America are made by indigenous communities through processes that preserve their traditions. Among these products is champús, a fermented drink or dessert native to Colombia, Ecuador, and Peru.
Yuli Lopez-Cadena   +2 more
doaj   +1 more source

Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes. [PDF]

open access: yes, 2009
Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health ...
Ju, Kou-San, Parales, Rebecca E
core   +1 more source

UPLC-MS/MS analysis of ochratoxin A metabolites produced by Caco-2 and HepG2 cells in a co-culture system [PDF]

open access: yes, 2017
Ochatoxin A (OTA) is one of the most important mycotoxins based on its toxicity. The oral route is the main gateway of entry of OTA into the human body, and specialized epithelial cells constitute the first barrier.
González Arias, Cyndia A.   +4 more
core   +2 more sources

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