Results 151 to 160 of about 11,278 (243)

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves   +3 more
wiley   +1 more source

Oxidative Stress Biomarkers in the Shrimp Macrobrachium amazonicum (Heller, 1862): Assessment in an Environmental Preservation Area in the Brazilian Amazon

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Anthropogenic activities generate a significant amount of pollutants that are released into the environment, causing physiological and ecological disturbances. Among the xenobiotics present in aquatic ecosystems, numerous chemical and organic compounds have oxidative potential or are metabolized through oxidative processes, which may amplify ...
Natália Eduarda da Silva   +6 more
wiley   +1 more source

Oxidative Damage, Energy Imbalance, and Behavioral Disruptions in Girardia tigrina Exposed to Treated Sewage Effluents

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas   +3 more
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou   +4 more
wiley   +1 more source

In vitro and in vivo metabolism profiles of cathinone and pseudoephedrine: Discrimination between khat and pseudoephedrine uses

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park   +6 more
wiley   +1 more source

Mycotoxins‐contaminated wheat matrices bioconversion by Tenebrio molitor larvae (Coleoptera: Tenebrionidae)

open access: yesInsect Science, EarlyView.
Larval development time, ADG, survival rate and substrate consumption were not negatively affected by the levels of mycotoxins contamination Larvae excreted most of the ingested DON and its derivatives through exuviae and frass The mycotoxin accumulation rates observed in larvae were always below the current legal limits for livestock feed Abstract ...
Valentina Candian   +4 more
wiley   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

open access: yesIntegrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu   +5 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

open access: yesThe FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz   +13 more
wiley   +1 more source

PFAS from a Discrete‐Event Terrestrial Source Migrates with Groundwater to Intertidal Seepages

open access: yesGroundwater, EarlyView.
PFAS is conveyed to the coastal intertidal zone from sources across the terrestrial landscape. Discharge of PFAS into the coastal ecosystem is complicated in space and time by the ongoing bi‐directional exchange of terrestrial groundwater and ocean water driven by tidal pumping within discharge areas.
Martin A. Briggs   +8 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

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